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dc.contributor.authorAied, Ahmed
dc.contributor.authorZheng, Yu
dc.contributor.authorPandit, Abhay
dc.date.accessioned2012-10-24T11:50:31Z
dc.date.available2012-10-24T11:50:31Z
dc.date.issued2012-02-02
dc.identifier.citationAied, A,Zheng, Y,Pandit, A,Wang, WX (2012) 'DNA Immobilization and Detection on Cellulose Paper using a Surface Grown Cationic Polymer via ATRP'. Acs Applied Materials & Interfaces, 4 :826-831.en_US
dc.identifier.issn1944-8252
dc.identifier.urihttp://hdl.handle.net/10379/3009
dc.descriptionJournal articleen_US
dc.description.abstractCationic polymers with various structures have been widely investigated in the areas of medical diagnostics and molecular, biology because of their unique binding properties and capability to interact with biological molecules in complex biological environments.; In this work-we report the grafting of a linear cationic polymer from an atom transfer radical polymerization (ATRP) initiator bound to cellulose paper surface. We show successful binding of ATRP initiator onto cellulose paper and grafting of polymer chains from the immobilized initiator with ATRP. The cellulose paper grafted polymer was used in combination with PicoGreen (PG) to demonstrate detection of nucleic acids in the nanogram range in homogeneous solution and in a biological sample (serum). The results showed specific identification of hybridized DNA after addition of PG in both solutions.en_US
dc.formatapplication/pdfen_US
dc.language.isoenen_US
dc.publisherAmerican Chemical Societyen_US
dc.relation.ispartofAcs Applied Materials & Interfacesen
dc.subjectAtom transfer radical polymerization (ATRP)en_US
dc.subjectDNA sensorsen_US
dc.subjectFluorescenceen_US
dc.subjectCationic polymersen_US
dc.subjectOligonucleotidesen_US
dc.subjectBiomarkersen_US
dc.titleDNA Immobilization and Detection on Cellulose Paper using a Surface Grown Cationic Polymer via ATRPen_US
dc.typeArticleen_US
dc.date.updated2012-10-18T17:01:30Z
dc.identifier.doiDOI 10.1021/am201483h
dc.local.publishedsourcehttp://dx.doi.org/10.1021/am201483hen_US
dc.description.peer-reviewedpeer-reviewed
dc.contributor.funder|~|
dc.internal.rssid2195942
dc.local.contactAbhay Shashikant Pandit, Mechanical & Biomedical Eng, College Of Eng & Informatics, Room 304, Nfb Building, Ida Bus Park, Dangan, Nui Galway. 2758 Email: abhay.pandit@oegaillimh.ie
dc.local.copyrightcheckedNo
dc.local.versionPUBLISHED
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