Browsing National Centre for Biomedical Engineering Science by Author "O Brien, Margaret"
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Differential expression of the metalloproteinase MMP3 and the a5 integrin subunit in human myometrium at labour
Ahamide, Elodie; Morrison, John J.; O Shaughnessy, Deirdre; O Brien, Margaret; Smith, Terry (Oxford University Press, 2007-09-13)Extensive tissue remodelling occurs in the human myometrium before, during and after parturition. The aim of this study was to investigate the expression of two tissue remodelling molecules, matrix metalloproteinase 3 ... -
Effects of combined progesterone and beta-estradiol treatment on the transcriptome of cultured human myometrial smooth muscle cells
Chandran, Sreenath; Cairns, Michael T.; O Brien, Margaret; O Connell, Enda; Mashayekhi, Kaveh; Smith, Terry (American Physiological Society, 2015)A transcriptomic analysis of cultured human uterine smooth muscle cells (hUtSMCs) was performed in order to examine gene expression profiles in smooth muscle in an environment containing the two major steroid hormones that ...