Browsing Research Institutes and Centres by Author "Marchese, Pietro"
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Diversity and bioactivity of fungi associated with the marine sea cucumber Holothuria poli: disclosing the strains potential for biomedical applications
Marchese, Pietro; Garzolib, Laura; Gnavib, Giorgio; O’Connell, Enda; Bouraouid, Abderrahman; Mehirie, Mohamed; Murphy, Mary; Varese, Giovanna Cristina (Society for Applied Microbiology (SfAM), 2020-04-10)Aims: Identification of the mycobiota associated to the marine echinoderm Holothuria poli and investigation of cytotoxic and pro-osteogenic potential of isolated strains. Methods and results: Fungal strains were isolated ... -
A novel high-throughput screening platform identifies itaconate derivatives from marine Penicillium antarcticum as inhibitors of mesenchymal stem cell differentiation
Marchese, Pietro; Mahajan, Nipun; O’Connell, Enda; Fearnhead, Howard; Tuohy, Maria; Krawczyk, Janusz; Thomas, Olivier P.; Barry, Frank; Murphy, Mary J. (MDPI, 2020-04-05)Worldwide diffused diseases such as osteoarthritis, atherosclerosis or chronic kidney disease are associated with a tissue calcification process which may involve unexpected local stem cell differentiation. Current ...