Browsing Research Institutes and Centres by Author "Irish Endocrine Society/Royal College of Physicians of Ireland"
Now showing items 1-3 of 3
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Burden of chronic kidney disease and rapid decline in renal function among adults attending a hospital-based diabetes center in Northern Europe
Griffin, Tomás P.; O'Shea, Paula M.; Smyth, Andrew; Islam, Md Nahidul; Wall, Deirdre; Ferguson, John; O'Sullivan, Esther; Finucane, Francis M.; Dinneen, Sean F.; Dunne, Fidelma P.; Lappin, David W.; Reddan, Donal N.; Bell, Marcia; O'Brien, Timothy; Griffin, Damian G.; Griffin, Matthew D. (BMJ Publishing Group, 2021-06-14)Introduction This study aimed to determine the prevalence of diabetic kidney disease (DKD) and rapid renal function decline and to identify indices associated with this decline among adults attending a diabetes center in ... -
Human mesenchymal stromal cells broadly modulate high glucose-induced inflammatory responses of renal proximal tubular cell monolayers
Islam, Md Nahidul; Griffin, Tomás P.; Sander, Elizabeth; Rocks, Stephanie; Qazi, Junaid; Cabral, Joana; McCaul, Jasmin; McMorrow, Tara; Griffin, Matthew D. (BMC, 2019-11-19)Background: Renal proximal tubular epithelial cells (RPTEC) are dysfunctional in diabetic kidney disease (DKD). Mesenchymal stromal cells (MSC) may modulate DKD pathogenesis through anti-inflammatory mediators. This study ... -
Plasma dephosphorylated-uncarboxylated Matrix Gla-Protein (dp-ucMGP): reference intervals in Caucasian adults and diabetic kidney disease biomarker potential
Griffin, Tomás Patrick; Islam, Md Nahidul; Wall, Deirdre; Ferguson, John; Griffin, Damian Gerard; Griffin, Matthew D.; O’Shea, Paula M. (Nature Research, 2019-12-05)Recent studies suggest a possible association between dephosphorylated-uncarboxylated MGP (dp-ucMGP) and glomerular filtration rate (GFR). This study aimed to establish normative data in an adult Caucasian population and ...