Browsing College of Engineering and Informatics by Author "Schaffler, M. B."
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Osteocyte differentiation is regulated by extracellular matrix stiffness and intercellular separation
Mullen, Conleth A.; Haugh, Matthew G.; Schaffler, M. B.; Majeska, R. J.; McNamara, Laoise M. (Elsevier, 2013-07-18)Osteocytes are terminally differentiated bone cells, derived from osteoblasts, which are vital for regulation of bone formation and resorption. ECM stiffness and cell seeding density have been shown to regulate osteoblast ...