Now showing items 1-3 of 3

  • Fluid flow in the osteocyte mechanical environment: a fluid-structure interaction approach 

    Verbruggen, Stefaan W.; Vaughan, Ted J.; McNamara, Laoise M. (Springer Verlag, 2013-04-09)
    Osteocytes are believed to be the primary sensor of mechanical stimuli in bone, which orchestrate osteoblasts and osteoclasts to adapt bone structure and composition to meet physiological loading demands. Experimental ...
  • Mechanisms of osteocyte stimulation in osteoporosis 

    Verbruggen, Stefaan W.; Vaughan, Ted J.; McNamara, Laoise M. (Elsevier, 2016-05-10)
    Experimental studies have shown that primary osteoporosis' caused by oestrogen deficiency results in localised alterations in bone tissue properties and mineral composition. Additionally, changes to the lacunar-canalicular ...
  • The role of integrin αVβ3 in osteocyte mechanotransduction 

    Haugh, Matthew G.; Vaughan, Ted J.; McNamara, Laoise M. (Elsevier, 2014-11-10)
    Recent in vivo studies have proposed that integrin alpha(v)beta(3) attachments between osteocyte cell processes and the extracellular matrix may facilitate mechanosensation in bone. However the role of these attachments ...