Browsing College of Engineering and Informatics by Author "McHugh, Peter"
Now showing items 1-9 of 9
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Biomodels of bone: a review
Lohfeld, Stefan; Barron, Valerie; McHugh, Peter (Springer, 2005)In this paper, a definition of a biomodel is presented, based on which different specific types of biomodels are identified, viz., virtual biomodels, computational biomodels, and physical biomodels. The paper then focuses ... -
A comparison of two quasi-static computational models for assessment of intra-myocardial injection as a therapeutic strategy for heart failure
Fan, Yiling; Ronan, William; Teh, Irvin; Schneider, Jurgen E.; Varela, Claudia E.; Whyte, William; McHugh, Peter; Leen, Sean B.; Roche, Ellen (Wiley, 2019-05-06)Myocardial infarction, or heart attack, is the leading cause of mortality globally. Although the treatment of myocardial infarct has improved significantly, scar tissue that persists can often lead to increased stress and ... -
Computational modelling of ovine critical-sized tibial defects with implanted scaffolds and prediction of the safety of fixator removal
Doyle, Heather; Lohfeld, Stefan; Durselen, Lutz; McHugh, Peter (Elsevier, 2015-01-14)Computational model geometries of tibial defects with two types of implanted tissue engineering scaffolds, β-tricalcium phosphate (β-TCP) and poly-ε-caprolactone (PCL)/β-TCP, are constructed from µ-CT scan images of the ... -
Computational study on the effect of contact geometry on fretting behaviour
McHugh, Peter; Zhang, Teng; Lean, Sean (Elsevier ScienceDirect, 2011-07-23)A key challenge in the design of engineering couplings and contacting components relates to the development of an understanding of the comparative performance of contrasting contact geometries for a given application, ... -
Effects of material thickness and processing method on poly(lactic-co-glycolic acid) degradation and mechanical performance
Shirazi, Reyhaneh Neghabat; Aldabbagh, Fawaz; Ronan, William; Erxleben, Andrea; Rochev, Yury; McHugh, Peter (Springer Verlag, 2016-09-02)In this study, the effects of material thickness and processing method on the degradation rate and the changes in the mechanical properties of poly(lactic-co-glycolic acid) material during simulated physiological degradation ... -
Fabrication, mechanical and in vivo performance of polycaprolactone/tricalcium phosphate composite scaffolds
Lohfeld, Stefan; Cahill, Senan; Barron, Valerie; McHugh, Peter (2012)This paper explores the use of selective laser sintering (SLS) for the generation of bone tissue engineering scaffolds from polycaprolactone (PCL) and PCL/tricalcium phosphate (TCP). Different scaffold designs are generated, ... -
A method to fabricate small features on scaffolds for tissue engineering via selective laser sintering
Lohfeld, Stefan; Tyndyk, M.A.; Cahill, S.; Flaherty, N.; Barron, Valerie; McHugh, Peter (2010)Purpose:Selective laser sintering (SLS) is a rapid prototyping technique applied to produce tissue-engineering scaffolds from powder materials. The standard scanning technique, however, often produces struts of extensive ... -
Micromechanical modelling of fatigue crack nucleation in stents
Sweeney, Caoimhe; McHugh, Peter; Leen, Sean B. (Bioengineering In Ireland Conference 2012, 2012)A finite element based micro-mechanical methodology for cyclic plasticity and fatigue crack initiation in cardiovascular stents is presented. The methodology is based on the combined use of a (global) three-dimensional ... -
Modelling the degradation and elastic properties of poly(lactic-co-glycolic acid) films and regular open -cell tissue engineering scaffolds
Shirazi, Reyhaneh Neghabat; Ronan, William; Rochev, Yury; McHugh, Peter (Elsevier, 2015-09-02)Scaffolding plays a critical rule in tissue engineering and an appropriate degradation rate and sufficient mechanical integrity are required during degradation and healing of tissue. This paper presents a computational ...