Browsing University of Galway Theses (PhD Theses) by Author "Sokol, Anna Magdalena"
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Roles of DNA polymerase eta and replication protein A (RPA) in undamaged and platinum-treated human cells
Sokol, Anna Magdalena (2012-09-28)Platinum-based drugs are widely used in cancer therapy. Bypass of platinum-induced DNA adducts during DNA replication by specialised DNA polymerases may contribute to drug tolerance and tumour cell resistance. Human cells ...