Browsing University of Galway Theses (PhD Theses) by Subject "Hydractinia"
Now showing items 1-6 of 6
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Cell fate commitment during nervous system establishment: from stem cells to neurons
(NUI Galway, 2020-07-06)Members of the early-branching metazoan phylum of Cnidaria are well-recognized as a sister group to bilaterians making them an ideal candidate to study the evolution of the eumetazoan nervous system. I began to unravel the ... -
Characterization of PIWI+ stem cells in Hydractinia
(2018-02-23)Hydractinia is a colonial marine invertebrate and a member of the phylum Cnidaria. It represents a very powerful tool for studying basic developmental biology and differentiation due to the presence of a population of stem ... -
Distinct mechanisms underlie oral versus aboral regeneration in the cnidarian hydractinia echinata
(2014-10-24)Distinct mechanisms underlie oral versus aboral regeneration in Hydractinia echinata. Head regeneration is preceded by stem cell migration, proliferation and blastema formation. After decapitation stem cells migrate from ... -
DNA methylation and zygotic genome activation during early embryogenesis of animals
(NUI Galway, 2020-10-25)Upon fertilization, after the fusion of two pronuclei, the newly formed zygotic genome is transcriptionally inactive. Hence, early animal development is driven by maternal RNAs and proteins. The zygotic genome becomes ... -
Transcriptome analysis in Hydractinia echinata reveals species-specific and phylum-wide gene loss
(NUI Galway, 2018-05-04)The advances and subsequent widespread use of next-generation sequencing, in particular transcriptomics, has allowed biologists to approach questions and study many more powerful and previously underappreciated model animals ... -
An unexpected role for Nanos in cnidarian neural stem cell fate determination
(2012-09)The mechanisms of lineage commitment and acquiring specific cell fate remain obscure and require investigating the role of particular genes involved in these complex processes. To address this issue, I studied the role of ...