Browsing University of Galway Theses (PhD Theses) by Subject "Colorectal cancer"
Now showing items 1-4 of 4
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Clinical Applications of Molecular Profiling in Colorectal Cancer
(2011-06)Despite developments in diagnosis and treatment, 20% of colorectal cancer (CRC) patients present with metastatic disease and 30% of cases recur after curative surgery. Furthermore, the molecular factors involved in prognosis ... -
Combining biological and chemical approaches in marine biodiscovery
(2017-06-13)Marine organisms are prolific producers of novel and structurally interesting metabolites. The identification of marine natural products contributes to many scientific areas including pharmacology, chemical ecology, chemical ... -
Exosomal microRNAs in colorectal cancer
(2016)Cancer cells have been shown to release a variety of extracellular membrane vesicles including microvesicles known as exosomes. Exosomes have recently been found to contain microRNAs (miRNAs) however the full range within ... -
The role of sialylation in stromal cell-mediated immunosuppression in the colorectal tumour microenvironment
(NUI Galway, 2023-04-19)Immunosuppressive tumour microenvironments (TME) inhibit the effectiveness of many immunotherapies. The hypersialylation of cancer cells contributes significantly to this suppressive environment, aiding in tumour immune ...