Browsing University of Galway Theses (PhD Theses) by Subject "Atherosclerosis"
Now showing items 1-4 of 4
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The Atherosclerotic Environment Accentuates Endochondral Ossification in Vessel-Derived Stem Cells: In-vitro and In-vivo Assessment
(2013-11-08)Vascular calcification, far from being a passive degenerative process, is now perceived as an active, highly organized cell-controlled event. The presence of a number of stem progenitor niches and/or lineages in the ... -
Development of a gene-eluting stent for the treatment of in-stent restenosis
(2016-05-12)In-stent restenosis (ISR) results from stent-induced arterial injury, characterized by a complex cascade of cellular and biochemical events. The removal of endothelium during an angioplasty procedure causes the underlying ... -
Experimental and computational investigation of atherosclerotic plaque biomechanics
(NUI Galway, 2019-11-22)The overall objective of this thesis is to provide new insights into the composition and biomechanical behaviour of atherosclerotic plaque. Experimental and computational analysis techniques are developed to investigate ... -
An investigation of the immunometabolic interactions of obesity
(2013-09-04)Human monocytes are classified as classical, intermediate and non-classical according to their surface expression of CD14 and CD16. They also represent precursors to atherogenic foam cells and macrophages in metabolically ...