Browsing University of Galway Theses (PhD Theses) by Subject "Anti-cancer"
Now showing items 1-4 of 4
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Barton esters for initiator-free radical cyclisation with heteroaromatic substitution and anti-cancer evaluation of benzo[e][1,2,4]triazin-7-ones
(2014-07-03)Chapter 1 provides a general introduction to Chapters 2-5. Homolytic aromatic substitution routes to alicyclic ring-fused azoles and diazoles is reviewed. A review of recent literature using the COMPARE program of the ... -
Hydrogen peroxide and hydrohalic acid mediated synthesis of halogenated benzimidazolequinones and anti-cancer evaluation of benzotriazinones
(NUI Galway, 2019-11-29)Chapter 1 provides a literature review of metal and metal-free oxidative annulations employed to access ring-fused benzimidazoles while highlighting their significance and application towards anti-tumour benzimidazolequinones. ... -
Iodine in Seaweeds - Physiological Significance and Implications for Climate and Health
(2013-01-18)Iodine-rich macroalgae inhabit the subtidal on coasts in temperate regions. The algae-driven release of iodine into the environment has major implications for the biogeochemical iodine cycle a ffecting atmospheric chemistry ... -
Small-molecule-based crosslinking and bioconjugation of biomolecules
(NUI Galway, 2020-01-10)Chapter 1: The chemical modification and bioconjugation of proteins is an expanding yet challenging area of chemical biology. The superior nucleophilicity of cysteine presents it as a uniquely reactive bioconjugation handle. ...