Browsing University of Galway Theses (PhD Theses) by Subject "Small molecules"
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Investigation of various ligand design approaches and synthesis of diverse heterocyclic bioactive compounds
(NUI Galway, 2019-09-27)Structure-based design and ligand-based design are one of the most common approaches used to develop new inhibitors against druggable protein targets in various human disorders. Mcl-1 is a protein belongs to Bcl-2 family ...