Browsing University of Galway Theses (PhD Theses) by Author "Ronconi, Luca"
Now showing items 1-4 of 4
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Metal-based dithiocarbamato glycoconjugates: a suitable strategy to target tumour glycolysis?
Pettenuzzo, Andrea (NUI Galway, 2019-03-11)Rapidly dividing tumour cells require higher amounts of nutrients and energy for their fast proliferation, and glucose is no exception (the so-called “Warburg effect”). Consequently, such increased demand of glucose by ... -
Metal-based glycoconjugates for the targeted anticancer chemotherapy
Titilas, Ioannis (NUI Galway, 2023-08-30)Rapidly dividing tumor cells require higher amounts of nutrients and energy to sustain their abnormal proliferation rates, and glucose is no exception. Glucose enters the cell by facilitated diffusion through the glucose ... -
Metal-based theranostic and therapeutic agents for the targeted treatment and imaging of tumors
Mehder, Rozan (NUI Galway, 2024-01-12)The present PhD thesis resulted from the undertaking of two separate research projects, both anyway being strictly related to the rational design of metal complexes with potential therapeutic and/or diagnostic ... -
A “two birds with one stone” approach to the targeted treatment and imaging of tumors: vitamin B12-functionalized metallotheranostic agents
Fotopoulou, Eirini (NUI Galway, 2021-06-04)Vitamin B12 (aka cyanocobalamin) is a vital nutrient characterized by very low bioavailability. Owing to their extremely high proliferation rates, tumor cells show increased demand for nutrients compared with healthy ones, ...