Browsing University of Galway Theses (PhD Theses) by Author "Dwyer, Róisín"
Now showing items 1-3 of 3
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Investigation of metallacarboranes as unexpected therapeutics against triple-negative breast cancer cells
Murphy, Neville (NUI Galway, 2023-10-03)Metallacarboranes have been shown to have very promising properties for biomedical applications, with some derivatives having already shown good results in a number of cancer subtypes. The ability to self-aggregate, ... -
Mesenchymal stem cell mediated delivery of Extracellular Vesicle (EV)-encapsulated microRNAs for the treatment of breast cancer
Gilligan, Katie (NUI Galway, 2020-08-04)Mesenchymal Stem Cells (MSCs) hold the ability to home to the site of the tumour and bypass the host immune system. Extracellular Vesicles (EVs) are thought to be a fingerprint of the parent cell and therefore MSC-EVs ... -
The role of genomic data in stratifying patients within predictive models for breast cancer survival outcome
King, Lydia (NUI Galway, 2024-04-15)Genomic instability (GI), defined as an increased tendency for genomic alterations to occur, is a common feature of cancers and is recognised as a “facilitating” hallmark of cancer. Genomic alterations include base ...