Browsing University of Galway Theses (PhD Theses) by Title
Now showing items 983-1002 of 2242
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Human dignity as a bar to bio-patentability in European Patent Law: An exposé and a novel reform paradigm
(NUI Galway, 2023-10-04)This research addresses a gap found in the literature which is that there is a lack of coherence about the standard of the fundamental, but under-defined, concept of human dignity in European patent law. This problem ... -
Human endogenous retrovirus K (HERV-K) in prostate cancer
(2016-08-08)Millions of years of infection by viral agents have left their mark on the human genome in the form of human endogenous retroviruses (HERVs). These retroelements integrated into our germline, became subject to Mendelian ... -
Human induced pluripotent stem cells as a model for neurodevelopmental disease
(2015-10-01)Abstract Autism spectrum disorders (ASD) are neurodevelopmental disorders which encompass a wide range of symptoms, including intellectual disability and delayed development, while the phenotype can range from mild to ... -
Human induced pluripotent stem cells as an in vitro model for autism spectrum disorder
(NUI Galway, 2022-08-23)Autism spectrum disorders (ASD) are neurodevelopmental disorders which encompass a wide range of symptoms, including intellectual disability and delayed development, while the phenotype can range from mild to severe. Genetic ... -
Human rights and foreign investment
(2015-03-27)This study details the mechanisms of a neoliberal ideology operative in the current international approach to foreign direct investment (FDI). It charts an increasing dependency on FDI within the process of international ... -
Human rights compliant decision-making in child protection: Lessons for Ireland from a comparative socio-legal case study analysis of Ireland, England and Germany
(NUI Galway, 2021-08-01)Children have a right to be protected from harm and the State is obliged to take measures to vindicate that right. The State may intervene in family life by restricting parental rights, removing a child into care or placing ... -
The Human Rights Triangle: Transnational Corporations, International Human Law and Regional Cooperation in the Context of Development
(2013-01-29)Following World War II, the allied powers sought to improve global financial stability and ensure that basic rights were codified and protected at the international level. The UN Charter and the Bretton Woods agreements ... -
Human stem cell modeling for amyotrophic lateral sclerosis
(NUI Galway, 2022-09-28)Amyotrophic lateral sclerosis (ALS) is a fatal and progressive neurodegenerative disease characterized by the loss of upper and lower motor neurons (MNs). Most ALS cases are sporadic, with no family history or known genetic ... -
Human stem cell modelling for heart disease of long QT syndrome
(NUI Galway, 2022-04-29)Sudden cardiac death (SCD) in otherwise healthy young people is a public health priority. Long QT syndrome (LQTS) is the commonest life-threatening cardiac arrhythmia contributing to SCD under 40 years old with an estimated ... -
Human trafficking and China: Past and present
(2014-06)The idea of human trafficking as a new and distinct problem, a modern form of slavery that entraps individuals without agency in their own countries and abroad, is a common perception that has popularised the usage of the ... -
A human-centered design of a connected health system for older adults
(2017-08-15)The work outlined in this thesis explores the design of Connected Health devices, analyses the user characteristics of older adults and suggests a design methodology which was then applied to the design of two elements ... -
Hurdles for computationalism: The many difficulties facing a computationalist theory of phenomenal consciousness
(NUI Galway, 2023-11-20)There are several things that might be called ‘computationalism’. The one most central to the philosophy of mind is a theory that attempts to answer what Chalmers calls the ‘hard problem’ of consciousness: how can it ... -
A Hybrid Framework for Querying Linked Data Dynamically
(2012-09-28)As of today, the Web has evolved to become the largest collection of information made available by mankind. Researchers and developers are continuously working on transforming this loosely connected data collection into ... -
Hybrid simulation of ethernet based intra-vehicle networks
(2016-12-09)As Advanced Driver Assist Systems (ADAS) increase in complexity, it becomes essential to be able to rapidly prototype and test these systems in a reproducible and reliable way. This work explores the problem of simulating ... -
Hybrid systems modelling aided by machine learning with applications in healthcare
(NUI Galway, 2018-03)Recent trends towards data-driven methods may require a substantial rethinking of the process of developing simulation models. For instance, Machine Learning (ML) has demonstrated great potentials for constructing new ... -
Hydrogen peroxide and hydrohalic acid mediated synthesis of halogenated benzimidazolequinones and anti-cancer evaluation of benzotriazinones
(NUI Galway, 2019-11-29)Chapter 1 provides a literature review of metal and metal-free oxidative annulations employed to access ring-fused benzimidazoles while highlighting their significance and application towards anti-tumour benzimidazolequinones. ... -
Hydrogeophysics of coastal aquifers - geophysical applications to the assessment of groundwater properties in coastal gravel and karst aquifers
(2017-05-19)Airborne, terrestrial and marine geophysics have been employed to examine coastal zone hydrogeology in two very different aquifer types in Ireland. Modelling of regional airborne electromagnetic data informed by ground-based ... -
Hydrolysis, methanogenesis and bioprocess performance during low-temperature anaerobic digestion of dilute wastewater
(2015-04-28)Anaerobic digestion (AD) technologies represent sustainable and appropriate systems for the treatment of organic wastewaters. Lettinga et al (1987) stated, "A satisfactory application to raw domestic sewage would represent ... -
Hygroscopicity of marine aerosol: Closure, long term observation and cloud condensation potential
(NUI Galway, 2021-09-18)Marine aerosols have a profound impact on the global climate system by scattering solar radiation and serving as seeds for cloud formation. However, the marine aerosols in current models are still poorly represented and ... -
Hypertextualized Virtual Environments: Dual-Mode User Interface Design
(2011-06-03)This thesis develops a novel strategy for accessing Hypertextualized Virtual Environments (HiVEs), integrated information spaces where symbolic (hypertext) and visual (3D graphics) data are simultaneously available and ...