Browsing University of Galway Theses (PhD Theses) by Title
Now showing items 896-915 of 2245
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Functional effects of inter-genome interactions on seed development in Arabidopsis thaliana
(NUI Galway, 2022-01-14)Plant seed size determination is of high economic interest for modern food production worldwide as many crops are mainly consumed in the form of seeds, such as rice, wheat or corn. Parental conflict and genomic imprinting ... -
Functional genomics of microrna- directed regulation of tumorigenesis in human cancer cells
(2011-09-30)In the past few decades, microRNAs emerged as key regulators of gene expression in many fundamental biological processes such as development and differentiation as well as diseases. There are thousands of microRNAs that ... -
Functional role of CCAN histone fold proteins in mitosis
(2012-05-31)Centromeres are chromosomal loci that direct segregation of the genome by specifying kinetochore assembly in mitosis and meiosis. Kinetochores are built upon centromeric chromatin, which contains the histone H3 variant ... -
Functional screening of human faecal microbiome metagenome library for glycoside hydrolase enzymes
(NUI Galway, 2020-04-24)Members of the human gut microbiota use glycoside hydrolase (GH) enzymes, such as sialidases, α-fucosidases and β-galactosidases to forage on host mucin glycans and dietary fibers. A human faecal metagenomic library was ... -
Fuzzy k-mers and their application to comparative genome assembly
(2013-10-22)The application of k-mer matching to problems in the field of bioinformatics is long established, with k-mer techniques underpinning standard heuristic approaches to sequence alignment and genome assembly. Despite their ... -
Gach díograis go deireadh: Bailiúchán náisiúnta an bhéaloidis i dTeileann, iardheisceart Thír Chonaill, 1935-1976
(NUI Galway, 2020-02-02)Sa tráchtas seo, dírítear ar shaothar Sheáin Uí Eochaidh (1913-2002) agus a líonra seanchaithe i dTeileann idir 1935-1976. Le linn dó a bheith ag obair mar bhailitheoir de chuid Choimisiún Béaloideasa Éireann (1935-1971), ... -
GaIII and ZrIV Complexes as Phosphatase Analogues
(2011-11-16)In purple acid phosphatase (PAP)-catalysed phosphate monoester hydrolysis, it is accepted that the ferric ion of the active site can mediate the reaction through Lewis acid activation of the substrate and through nucleophilic ... -
Galway Grammar School, c. 1673-1958: A Foundation Institution of the Erasmus Smith Trust
(NUI Galway, 2019-05-02)This thesis is concerned with Galway Grammar School, from its opening about 1673 to its closure in 1958. It provides a broader understanding of Protestant grammar school education, particularly as it operated on the periphery ... -
Gearaltaigh Dheasmhumhan mar Phátrúin agus mar Údair i Réimse Léann agus Litríocht na Gaeilge
(2016-09-16)Sa tráchtas seo pléitear an phátrúnacht a dhein na Gearaltaigh, Iarlaí Dheasmhumhan, ar theaghlaigh léannta na hÉireann agus an caidreamh a bhí ag an teaghlach sin le léann agus cultúr na Gaeilge sna meánaoiseanna déanacha. ... -
Gender equality in UN peacekeeping: Fact or fiction? A review of the implementation of UNSCR 1325 via gender mainstreaming in three UN operations
(NUI Galway, 2022-04-26)The year 2020 marked the 20th anniversary of UN Security Council Resolution (UNSCR) 1325, on Women, Peace and Security (WPS). The resolution recognised the invaluable role women play in the prevention and resolution of ... -
Generating and ranking candidate data models from background knowledge
(NUI Galway, 2021-01-04)Knowledge graphs have emerged as a core technology to publish, share, and integrate data on the Web. Contrary to traditional data storage solutions, such as relational databases, one of the core functionalities of Knowledge ... -
Generation of natural killer cell-mimic nanoparticles to target tumour cells
(NUI Galway, 2022-05-30)Natural killer (NK) cells are effector immune cells in the innate immune system. It is increasingly recognised that NK cells play a crucial role eliminating emerging tumour cells. Some tumour cells however can escape and ... -
Generation of recombinant anti-N-glycolylneuraminic acid (Neu5Gc) scFv and its applications for detection and quantitation of Neu5Gc
(2016-05-12)Sialic acids are a family of 9 carbon α-keto acid monosaccharides. Owing to their terminal position on glycans, sialic acids are involved in cell adhesion and recognition events, host pathogen interactions, immune regulation ... -
Generational understanding of social support, youth civic engagement and coping as aspects of resilience in socialist and post-socialist Slovenia (1980-2011)
(2015-09-30)This thesis explores the link between protective factors and youth coping as aspects of resilience within the context of social change. The most recent evidence from resilience research shows there is a significant link ... -
The genesis of the Europeanisation of the Northern Ireland peace process
(2018-01-17)The thesis examines the economic and political contributions of the European Union (EU) to the Northern Ireland peace process, tracing the genesis of EU involvement and analysing how it acted as an arena in which to ... -
Genesis of the Moly Brook molybdenum-copper deposit, Newfoundland, Canada: Geological and geochemical constraints on fluid evolution, links with adjacent tungsten mineralization, and the role of Late Devonian granitic intrusions
(NUI Galway, 2017-08-25)An integrated geological, structural and geochemical study of the Moly Brook Mo-Cu deposit, southern Newfoundland (Canada), is presented. The role of subordinate leucogranite as progenitor to the mineralizing components ... -
Genetic analysis of ATR, a central regulator of genome stability.
(2016-05-11)To protect the DNA against the constant assaults of endogenous and environmental agents, cells have developed conserved signaling pathways, known as the DNA damage response. Such responses are important to maintain genome ... -
Genetic analysis of carotenoid accumulation in tropical maize inbred lines using molecular tools and field tests for accelerating the biofortification of maize with provitamin A
(2015-05-13)Improving the nutritional content of staple crops through breeding (biofortification) is promoted as cheap and sustainable approach for alleviating vitamin A and other micronutrient deficiencies across the world. Maize is ... -
Genetic and biotechnological development of the pennate marine diatom Phaeodactylum tricornutum for high-value bioproducts and carbon bio-mitigation.
(2014-04-25)Conflicting demands of food over fuel and the mushrooming need for feed and fibre are serious challenges for humankind at a time when we also need to address climate change challenges. Global demands for land based commodities ... -
Genetic basis for dosage sensitivity of seed size heterosis in Arabidopsis thaliana
(NUI Galway, 2021-09-08)Heterosis refers to the ability of the F1 offspring to display superior characteristics compared with their parents and despite being genetically studied since the early 1900s, many aspects of this phenomenon remain unclear. ...