Browsing University of Galway Theses (PhD Theses) by Title
Now showing items 474-493 of 2239
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Development and characterisation of recognition molecules for the specific identification of non-human glycans
(2015-01-26)Glycosylation is an enzymatic process through which glycans attach to proteins, lipids and other organic molecules with huge structural diversity. This is a common post-translational modification found on proteins and cell ... -
Development and evaluation of an assessment tool for identification of elements of situation awareness in OSCEs in undergraduate medical curricula
(NUI Galway, 2018-07-20)Situation awareness (SA) is recognised as an important factor in patient safety and clinical decision making in conjunction with diagnostic and therapeutic reasoning. Missed diagnosis and treatment errors have been identified ... -
Development and evaluation of an online hypnosis programme for the treatment of migraine
(NUI Galway, 2018-10-17)This study examined the development and evaluation of an online hypnosis programme for the treatment of migraine. 43 participants who suffered with two or more migraines a month and who satisfied other study criteria ... -
Development and evaluation of an online version of the Feeling Better pain management programme for children and their care-givers
(NUI Galway, 2019-10-08)Abstract Background: Reasons for poor management of paediatric chronic pain include lack of access to psychological support for pain management. Research evidence is increasingly focused on online interventions as a ... -
Development and evaluation of platform-based SERS substrates for detecting cancer biomarkers at ultra-low concentrations
(2017-04-27)Surface Enhanced Raman Scattering (SERS) has proved to be a powerful spectroscopic tool since its discovery in 1973. Advances in nanofabrication techniques increasingly allow for the manufacture of complex nanostructured ... -
Development and Implementation of an Ultra High Speed Astronomical Polarimeter: The Galway Astronomical Stokes Polarimeter (GASP)
(2013-05-12)Optical polarization is a powerful diagnostic tool in astrophysics, allowing the investigation of asymmetries in source regions of astronomical objects, magnetic field configurations, and magnetic field strengths. Polarized ... -
Development and optimisation of an oxygen-based amendment for cattle slurry designed to reduce methane emissions during storage
(NUI Galway, 2023-11-07)Methane (CH4) is a potent greenhouse gas (GHG) that is produced via anaerobic digestion in slurry storage facilities, which are ubiquitous in farming systems with animal husbandry. Globally, CH4 emissions from agriculture ... -
Development and Psychometric Evaluation of a Scale to Assess Sexual Difficulties in Gay Men
(2013-12-20)A sexual difficulty or dysfunction has been defined as the disturbance or inadequacy of normal sexual responding (Rowland, 2007). The Diagnostic and Statistical Manual for Mental Disorders (DSM-5; American Psychiatric ... -
Development and testing of behaviour change based intervention for machine related safety on farms
(NUI Galway, 2024-04-15)Background Farm machinery-related injuries are a growing concern worldwide, posing serious risks to farmers' safety and leading to severe disabilities or fatalities. As the farming population ages and farming machinery ... -
The development and validation of a measure assessing gender role conflict in male adolescents
(2014-01-08)The purpose of these studies was to develop a psychometrically sound questionnaire that addresses outstanding empirical issues in adolescent gender role conflict and, in so doing, enhance understanding of the negative ... -
Development of 3D breast cancer model to study extracellular vesicle crosstalk
(NUI Galway, 2024-01-31)3D model systems are crucial in establishing novel therapeutics and understanding cell interactions in the tumor microenvironment. Extracellular vesicles (EVs) are promising carriers of therapeutic cargo for tumor-targeted ... -
Development of a Chemical Kinetic Mechanism for Small Hydrocarbons
(2014-01-07)A detailed chemical kinetic mechanism has been developed to describe the oxidation of small hydrocarbon and oxygenated hydrocarbon species. In order to understand the oxidation of large hydrocarbon and oxygenated hydrocarbon ... -
The Development of a Computational Test-Bed to Assess Coronary Stent Implantation
(2013-03-15)The implantation behaviour of coronary stents is of great interest to clinicians and engineers alike as in-stent restenosis (ISR) remains a critical issue with the community. ISR is hypothesized to occur for ... -
The development of a digital intervention to promote timely presentation of breast cancer symptoms to a healthcare professional
(NUI Galway, 2019-10-31)Breast cancer is the primary cause of death among women globally and in Ireland, mortality rates from breast cancer are the third highest in Europe. Early diagnosis of breast cancer is linked to more favourable outcomes ... -
Development of a dual-hit model of Parkinson's disease by combining environmental and genetic risk factors
(2012-06-06)Even though half a century has passed since the discovery of the efficacy of the dopamine precursor, levodopa, it remains the most effective therapy for the motor symptoms of Parkinson's disease to this day, despite its ... -
Development of a fundus camera with adaptive optics using a pyramid wavefront sensor
(2012-03-02)This PhD thesis presents the building of an adaptive-optics system based on a pyramid wavefront sensor applied to the imaging of the human retina (fundus) in vivo. The instrument aims to simultaneaously measure the ocular ... -
Development of a gene-eluting stent for the treatment of in-stent restenosis
(2016-05-12)In-stent restenosis (ISR) results from stent-induced arterial injury, characterized by a complex cascade of cellular and biochemical events. The removal of endothelium during an angioplasty procedure causes the underlying ... -
Development of a global energy management system for the non-energy intensive multi-site manufacturing organisations
(NUI Galway, 2018-09-30)Climate change and energy resource sustainability are both major challenges facing humanity today. Due to their scale, multi-site (and/or multi-national) manufacturing organisations (MMO), are large consumers of energy, ... -
Development of a high throughput screening strategy for drug discovery: from marine fungi to stem cell applications
(NUI Galway, 2021-08-04)Chemical compounds synthetized by living organisms have historically contributed to improved human health. Ancient populations made use of local natural products through herbal medicine, which today are to be found as ... -
Development of a high time resolution optical polarimeter for astronomy
(NUI Galway, 2018-12-17)This work started in September, 2014 and initially started as an investigation of the characterisation issues associated with using Electron Multiplying Charge- Coupled Devices (EMCCDs) in a two beam polarimeter. It was ...