Browsing University of Galway Theses (PhD Theses) by Title
Now showing items 434-453 of 2244
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Design and synthesis of novel constrained glycomimetics as inhibitors of galectins and galactosidases
(NUI Galway, 2023-10-10)Chapter 1 gives a brief introduction to carbohydrate structure, discussing factors influencing reactivity and conformation, such as the anomeric and exo-anomeric effect. Chapter 1 mentions methods of structural analysis ... -
Design Exploration of EMBRACE Hardware Spiking Neural Network Architecture and Applications
(2014-02-05)The operation and structure of the human brain has inspired the development of next generation smart embedded computing systems. The cognitive abilities of the human brain have been partially explained by the dense and ... -
Design of fibre-reinforced polymer composite blades for wind and tidal turbines
(2017-09)There is substantial opportunity in the development of wind and tidal current turbines to help decarbonise national energy systems and to expand the economic potential of the European Union. However, well-documented cases ... -
Design thinking capability model: A management framework to support design thinking implementation for product development
(NUI Galway, 2019-10-08)Design thinking is lauded to reduce cost and redesign work in the new product development process and shorten lead time to development. Because of that, researchers are investigating how to use using design thinking as ... -
Design, analysis and testing of a spiral blade vertical-axis tidal turbine
(NUI Galway, 2021-05-04)The aim of this thesis is to develop a combined analytical, computational and experimental methodology for characterisation and optimisation of the hydrodynamic performance of a novel vertical-axis tidal turbine concept. ... -
Design, development and validation of a series of multiplex real-time PCR diagnostics assays for the rapid and accurate detection and differentiation of the Mycobacterium tuberculosis complex
(2012-03-01)Tuberculosis (TB) remains a major health concern both in developed and developing countries due to the high rates of morbidity and mortality associated with disease. In humans, TB is caused by members of the Mycobacterium ... -
The Design, Development and Validation of a Wearable Behaviour Monitor for the Autonomous Assessment of the Functional Health of Older Adults
(2013-12-23)Functional ability describes a person's capability to perform those tasks that are necessary to live independently. It is a proven predictor of functional decline, the need for hospitalisation and institutionalisation ... -
The design, manufacture and testing of a composite polysialic acid mimetic peptide loaded collagen nerve graft for use in peripheral nerve repair
(NUI Galway, 2016-02-15)Peripheral nerve injuries can be debilitating for patients. The current gold-standard technique for peripheral nerve repair is autograft. This procedure involves harvesting a non-critical nerve from a donor site from the ... -
Design, synthesis and catalytic activity of novel oxazoline based ligands
(2015-08-14)This thesis can be viewed as two separate studies. Firstly, the design, synthesis and catalytic activity of novel 2-pyridyl mono(oxazoline). A family of mono(oxazoline) ligands were developed in which the 5-poition is ... -
Design, synthesis and evaluation of glycomimetics as galectin inhibitors
(NUI Galway, 2024-03-11)Chapter-1: This chapter begins with a short review on carbohydrates and their structure and then summarises some highlights from the last two decades of research on developing carbohydrate-based drug candidates. Included ... -
Design, synthesis, and public understanding and involvement in randomised trials
(NUI Galway, 2021-03-16)Introduction The initial aim of my PhD was to assess if amniotic membrane sweeping, a common intervention in maternity care, is a safe and effective way of preventing a formal induction of labour1 in pregnant women at ... -
Designing blended learning for accounting in tertiary education: The PACE-IT model
(NUI Galway, 2020-10-29)Technological advancements have engendered evolving work roles for professional accountants as they navigate the trajectory of their careers. This has prompted calls for the transformation of accounting education at ... -
Designing digital storytelling: creative technology for reflection in initial teacher education
(2014-03-03)Reflection represents a foundational, core developmental activity in teacher professional education. Reflection can, however, prove challenging, and even problematic, particularly for novice, pre-service teachers (Calderhead, ... -
Desmosomal armadillo proteins in zebrafish cardiac development
(2012-12-18)Plakoglobin and plakophilin-2 are desmosomal armadillo proteins, required for correct cardiac development in zebrafish. Mutations in the human genes can cause the congenital heart defect arrhythmogenic right ventricular ... -
Detecting seen/unseen objects with reducing response time for multimedia event processing
(NUI Galway, 2021-09-01)The enormous growth of multimedia content in the domain of the Internet of Things (IoT) leads to the challenge of processing multimedia streams in real-time. Thus, the Internet of Multimedia Things (IoMT) is an emerging ... -
Detection and characterisation of partially occluded vulnerable road users
(NUI Galway, 2023-10-29)Accurate detection and classification of vulnerable road users (pedestrians, cyclists, and micro-mobility users) is a safety critical requirement for the deployment of autonomous vehicles in heterogeneous trac. Object ... -
The detection and tracking of people in meeting contexts using image processing
(NUI Galway, 2019-11-14)Image processing techniques for object detection and tracking using a top-view camera are presented in this thesis. Finding reliable object features, especially in an environment when distinctive object features are not ... -
Detection of faint exoplanets in multispectral data
(NUI Galway, 2019-04-15)The detection of extrasolar planets is extremely difficult due to their extreme faintness and proximity to their parent stars. Direct, ground-based detection is particularly challenging and despite the incredible contrast ... -
Detection of vehicles using fisheye cameras
(2017-05-10)An image processing system capable of detecting vehicles within the vicinity of the ego vehicle for use in a surround view camera system (SVC) is presented in this thesis. Image processing based object detection can be ... -
Detention without trial in the United Kingdom: From empire to the 'War on Terror'
(2014-05-16)This thesis analyses detention without trial in the United Kingdom by applying a socio-legal lens to several instances where these extra-judicial powers have been adopted. What will emerge from this examination is twofold. ...