Browsing University of Galway Theses (PhD Theses) by Title
Now showing items 169-188 of 2238
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Biodiversity and performance of constructed wetlands; a comparison with natural wetlands
(NUI Galway, 2018-07-03)Natural wetlands (NWs) are one of the most economically and ecologically important habitats on Earth, currently comprising about 6% of the world’s surface area. They provide many ecosystem services including the supply of ... -
Bioelectrochemical films on electrodes for application to biofuel cells
(2012-05-04)This thesis focuses on studies of both enzymatic (EFC) and microbial (MFC) fuel cells. In the enzymatic fuel cell studies, interactions between enzymes, osmium based complexes and redox polymers are characterized ... -
Bioethanol and biobutanol production from CO and CO2 using solventogenic acetogens
(NUI Galway, 2022-01-27)This research aimed at enhancing ethanol and butanol production from H2/CO2 and CO by anaerobic sludge from wastewater treatment plants via investigating the environmental parameters in a semi-gas fed bioreactor and ... -
Biofilms on electrodes and crosslinking of bovine pericardium tissue : application to biopower device development and anti-calcification of bioprosthetic valves
(2017-11-24)Advances in the electrical communications between enzymes and electrodes made it possible to the fabrication of new miniaturized implantable power devices. This thesis is devoted to study and improvement of enzyme electrodes ... -
Biofortification for better nutrition: developing and delivering crops with more impact
(NUI Galway, 2020-05-06)Background: Globally, around three billion people have inadequate diets and are often malnourished. Biofortification, a nutrition-sensitive approach that aims to increase the nutritional density of staple crops, has great ... -
Biogas clean-up using a novel hollow fibre membrane bioreactor for end-use applications
(NUI Galway, 2022-04-06)The aim of this research was to develop a novel hollow fibre membrane bioreactor (HFMB) that can be used for H2S laden waste gas treatment and biogas desulfurization. In addition, the aim was to utilize the HFMB for ... -
A bioinformatic approach to the genetics, human cell models and animal models of autism spectrum disorder
(NUI Galway, 2021-09-17)Autism Spectrum Disorder (ASD) is a group of complex neurodevelopmental disorders with diverse clinical manifestations and symptoms. In the last 10 years, there have been significant advances in understanding the genetic ... -
Bioinspired micropatterned adhesive surfaces for medical applications: a numerical investigation of fibrillar adhesives and swellable microneedle arrays
(NUI Galway, 2024-03-21)Traditional sutures and tissue adhesives can cause adverse effects, inflicting additional damage to the tissue, resulting in toxic chemical residues, and increasing the risk of infection. Bioinspired adhesives have ... -
Biological and chemical analysis of azaspiracids and amphidinols originating from dinoflagellate strains associated to Irish waters
(NUI Galway, 2024-04-15)Microalgae have the potential to produce biologically active metabolites which can be toxic, affect our fisheries and endanger food safety. Due to their active nature these toxins can also have therapeutic benefits when ... -
A biological and pharmacological investigation of the unfolded protein response in models of breast cancer
(NUI Galway, 2020-11-20)Breast cancer is the most common malignancy in women worldwide. At the molecular level, breast cancer is a heterogeneous disease. For example, the claudin low subtype of breast cancer is characterised by epithelial-mesenchymal ... -
Biological characterization of a human mesenchymal stromal cell product
(2016-07-21)The translation of stem cell research into a therapeutic setting presents with it many scientific, logistic, financial and regulatory challenges for academic scientists. This thesis identifies some key areas that one must ... -
The biology of the slug-killing Tetanocera elata (Diptera: Sciomyzidae) and its potential as a biological control agent for pestiferous slugs
(15-02-05)Laboratory experiments were carried out to determine the effects of controlled temperatures (14oC, 17oC, 20oC, 23oC, and 26oC) and ambient outdoor and laboratory temperatures on the development and predation capacity of ... -
Biomaterial scaffolds and genetically modified stem cells - An Investigation of their potential in bone repair
(2017-10-10)The task of repairing large sections of bone tissue lost due to major trauma or pathology poses a significant challenge in orthopedic healthcare. The medical intervention often resorted to consists of a combination of ... -
A Biomaterials Approach for an Ex-Vivo Multiple Sclerosis Model of Inflammatory Demyelination
(2013-10-03)Multiple sclerosis (MS) is characterised by the presence of inflammatory demyelinating foci throughout the brain and spinal cord, accompanied by axonal and neuronal damage. Although inflammatory processes are thought to ... -
Biomaterials approach for targeted therapeutics delivery in inflammatory bowel disease
(NUI Galway, 2021-01-25)Pathogenesis of inflammatory bowel diseases (IBD) is associated with continuous episodes of diffusive gut epithelial inflammation and dysregulated mucosal immune response. IBD (with major forms Crohn’s and ulcerative ... -
A biomaterials approach to peripheral nerve repair
(2014-04-09)Peripheral nerve injuries are a major clinical problem which currently affect over one million people worldwide. Transection injuries caused by workplace and home injuries, road traffic accidents and by intentional harm ... -
Biomimetic nano-biomaterials for bone repair and regeneration
(2017-02-24)Currently, over 1.7 billion people suffer from a musculoskeletal disorder; over 200 million operations take place annually; and in excess of 1 million new clinical cases are reported per year. Further, the annual healthcare ... -
Biophysical and biochemical microenvironmental cues for tenogenic phenotype maintenance, differentiation and trans-differentiation in vitro
(NUI Galway, 2019-07-19)Tendon injuries affect tens of millions of people worldwide each year and as the average lifespan increases their occurrence also increases, Achilles rupture rates alone have increased by ≈ 1000% in the last 40 years. ... -
Biophysical and biochemical tools for cell phenotype maintenance, differentiation and trans-differentiation
(NUI Galway, 2018-02-22)Tendon injuries constitute an unmet clinical need, with 3 to 5 million new incidents occurring annually worldwide. Tissue grafting and biomaterial-based approaches fail to provide environments that are conducive to ... -
Bioprocess monitoring using Polarised Multidimensional Fluorescence (pMDF) spectroscopy
(NUI Galway, 2022-06-15)Bioprocess monitoring is essential for biopharmaceutical manufacturing as it helps to ensure the required quality of the therapeutic proteins and maximise the productivity of the bioprocess as per Quality-by-Design (QbD) ...