Browsing University of Galway Theses (PhD Theses) by Title
Now showing items 1220-1239 of 2244
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Isolation and characterisation of immune modulatory extracellular vesicles from CD362-selected human umbilical cord mesenchymal stromal cells
(NUI Galway, 2021-07-28)Mesenchymal stromal cells (MSCs) exert numerous therapeutic effects, including immunomodulatory and anti-inflammatory effects in vitro and in vivo, which are being explored as a treatment for many unmet medical needs. These ... -
Isolation and characterisation of novel stromal cell populations from human bone marrow
(2012-11-13)Mesenchymal stem cells (MSCs) hold great promise for application in the field of regenerative medicine due to their multipotent capacity and immuno-regulatory potential. Paramount to their implementation in the clinic is ... -
‘It was in the Air’: Micro and macro flows in the changing soundscape of Irish traditional music in Galway, 1961 to 1981
(NUI Galway, 2024-04-18)This thesis investigates the emergence of a vibrant Irish traditional music scene in Galway City and explores changes in its soundscape, from 1961 to 1981. Changes in the world of traditional music, embedded in Irish ... -
It's in the details the divil is: Corpus linguistics and Irish English literary dialect
(2014-12-08)Scholars of literary dialect have often found themselves defending the focus of their study against allegations of exaggeration and stereotyping, particularly in areas like Ireland, where a legacy of colonialism and of ... -
It’s My Life! Decision-making for children and young people with disabilities in Ireland and Article 12 of the UN Convention on the Rights of Persons with Disabilities
(NUI Galway, 2023-05-18)Article 12 of the UN Convention on the Rights of Persons with Disabilities (CRPD) affirms that persons with disabilities have the right to make decisions on an equal basis with others. To achieve this, States Parties ... -
James Larkin and the British, American and Irish Free State Intelligence Services: 1914-1924
(2016-02)This thesis takes the form of a case study and is an investigation of the activities of James Larkin between October 1914 and June 1924. It is an analysis of how capitalist states dealt with Larkin in the context of his ... -
John McGahern's house of vision: From darkness to the rising sun
(NUI Galway, 2020-11-17)John McGahern (1934-2006) believed that books could act as mirrors. They can also act as windows on the world. Such windows, however, necessarily frame our fields of vision, alter and shape our perspectives. Far from being ... -
Judicial pro-activism and collaborative constitutionalism: Ensuring environmental justice in India, Ireland, and Bangladesh
(NUI Galway, 2022-09-29)This is a doctrinal, comparative, and socio-legal analysis examining the role of the courts of India, Ireland, and Bangladesh in environmental matters. Considering the challenges they face, this thesis proposes and constructs ... -
Just tweet it - The collection, processing, classification and analysis of 2 million fitness tweets
(NUI Galway, 2018-06-13)In 2013, the World Health Organization coined the term “Globesity” to highlight the importance of the epidemic and impact as a major health problem in many parts of the world (World Health Organization, 2013). Many believe ... -
The Kantian foundation of Aby Warburg’s theory of culture: An interpretation of the concept of orientation
(NUI Galway, 2021-05-05)The aim of this work is to provide an interpretation of Aby Warburg’s scholarship highlighting its connections with Kant’s philosophy in order to offer a more systematic account of its scope and principles. Although it is ... -
KIF18B, a nuclear kinesin, is involved in DNA damage response
(NUI Galway, 2021-03-08)DNA damage from both exogenous and endogenous sources occurs continuously in all cells. A multitude of DNA repair mechanisms have evolved to maintain genome stability. The 53BP1 tumour suppressor has been identified as a ... -
A kind of mime: Cultural politics and narrative experiment in the works of Samuel Beckett, Máirtín Ó Cadhain, and Brian Ó Nualláin
(NUI Galway, 2019-09-27)This thesis is a trilingual comparative literary study, analysing the works of Samuel Beckett (1906-1989), Máirtín Ó Cadhain (1906-1970), and Brian Ó Nualláin (1911-1966). This study will argue that the very particular ... -
The kinesin KIF18B interacts with 53BP1 and is required for efficient double strand break repair
(2015-11-19)Genetic changes can lead to detrimental genomic instability, mutagenesis, oncogenesis and premature aging. The DNA damage response (DDR) is responsible for safeguarding the genome from such harmful alterations. 53BP1 ... -
Knowledge extraction from simplified natural language text
(NUI Galway, 2019-10-08)Knowledge base creation and population are an essential formal backbone for a variety of intelligent applications, decision support and expert systems and intelligent search. Although knowledge extraction from ... -
Knowledge graph mining with latent shape graphs
(NUI Galway, 2020-07-21)Knowledge graphs are graph-structured knowledge bases that have shown to be of great value in many Artificial Intelligence applications in academia and industry alike. They are typically generated automatically from un-/semi- ... -
Knowledge-based multi-objective multi-agent reinforcement learning
(2017-08-17)Multi-Agent Reinforcement Learning (MARL) is a powerful Machine Learning paradigm, where multiple autonomous agents can learn to improve the performance of a system through experience. The majority of MARL implementations ... -
L'e-learning nella glottodidattica: strumenti e proposte in una prospettiva connettivista
(2011-10-28)E-learning can certainly be considered an aspect of education in its broad meaning, although it implies that the learner is situated at a physical distance from the instructor and therefore the use of a computer (or other ... -
La Habana as a site of disenchantment in the work of Leonardo Padura Fuentes
(2013-09-27)This thesis establishes that disenchantment in the city of La Habana is a recurring theme in the narrative of Cuban author Leonardo Padura Fuentes. It involves a close reading of seven novels written and published between ... -
De la promotion et protection des droits humains dans le contexte du VIH/SIDA: facteur limitant l'extension de l'épidémie? (The Promotion and Protection of Human Rights in the Context of HIV/AIDS: a Factor limiting the Growth of the Epidemic?)
(2011-10-21)The HIV/AIDS pandemic has reached historical heights. The number of infected people has been rising constantly and the HIV crisis has been spreading to more and more countries. Testimony to this is the higher number of ... -
Labour agency and the Dubai Irish
(NUI Galway, 2021-03-09)An Irish community has been established in Dubai since 1974, with a surge in those migrating from Ireland to Dubai during the Great Recession (2008-2014). Since 2014 the approximate number of Irish migrants has increased ...