Browsing University of Galway Theses (PhD Theses) by Title
Now showing items 1051-1070 of 2244
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Impacts of DNA damage on the pericentriolar material and centriole duplication
(2015-12-03)The centrosome consists of two barrel-shaped centrioles embedded in a proteinaceous pericentriolar material (PCM), a highly organised scaffold that serves as a platform for proteins that regulate spindle assembly, protein ... -
Impacts of natural and induced abiotic factors on phlorotannins in brown algae
(2018-02-22)Phlorotannins are a group of highly bioactive marine polyphenols found exclusively in brown algae. They play multiple ecological roles in algae inhabiting stressful environments and, as a result, their natural concentrations ... -
IMPAIR: Massively parallel regularised Richardson-Lucy deconvolution on heterogeneous hardware
(2017-10-27)This thesis investigates the comparative performance of multicore CPU and general purpose GPU on a commodity desktop computer. To investigate this, an image deconvolution software package (IMPAIR) was updated from its ... -
Implementation of menu labelling interventions in the out-of-home food environment
(NUI Galway, 2022-10-10)Background: Prevention of obesity is a public health priority both globally and in Ireland. While the causes of obesity are complex and multifaceted, poor diet is a leading risk factor. Labelling menus with nutrition ... -
Implementation strategies for the use of social robotics in the context of dementia
(NUI Galway, 2022-12-14)Introduction Dementia is a global health challenge, and the number of people living with dementia (PLWD) is expected to continue to rise worldwide. Pet robots have been developed to support the psychosocial well-being ... -
Implications of histone H2AX abundance in breast cancer
(NUI Galway, 2019-12-09)Histones are responsible for the packaging of DNA into a eukaryotic cell nucleus, and the H2A variant H2AX plays an important role in the DNA damage response (DDR). The phosphorylated form of H2AX, known as γH2AX, has been ... -
The importance of a continuum of care before, during and after pregnancy in women with type 1 and type 2 diabetes along the Irish Atlantic seaboard
(2017-04-06)Pregestational diabetes is the most common chronic medical condition to complicate pregnancy and is associated with an increased risk of morbidity and mortality for the mother-offspring pair. Optimising outcomes for this ... -
Importance of the caregiver in lifestyle interventions for cognitive impairment
(NUI Galway, 2022-04-11)Lifestyle risk factors have been identified as key targets for dementia prevention strategies, with most clinical trials targeting individual-level interventions. However, many lifestyle behaviours are known to cluster ... -
Improved cardiac arrhythmia prediction based on heart rate variability analysis
(NUI Galway, 2021-05-10)Many types of ventricular and atrial cardiac arrhythmias have been discovered in clinical practice in the past 100 years, and these arrhythmias are a major contributor to sudden cardiac death. Ventricular tachycardia, ... -
Improved jitter buffer and playout management approach
(NUI Galway, 2020-10-06)The popularity and adoption of Voice over Internet Protocol (VoIP) communications have risen at an unprecedented level in the recent decade as an alternative to conventional telephony technologies, such as Public Switched ... -
Improved techniques for time synchronisation over WiFi and wireless sensor networks
(2013-10-23)Time synchronisation plays a key and ever increasing role in this progressively networked world. Whilst time synchronisation has always been important in industrial and telecommunication systems, its importance has now ... -
Improvement of sludge dewaterability using filamentous fungi and energy recovery from thermal treatment of sludge
(NUI Galway, 2022-06-20)Nowadays, the increasing production of municipal sludge requires effective and suitable disposal methods. The commonly used methods include thickening, dewatering, anaerobic digestion, composting, and thermal treatment. ... -
Improving flow in large software product development organizations: A sensemaking and complex adaptive systems perspective
(NUI Galway, 2019-08-23)Software development organizations operate in an environment of ever-increasing volatility, uncertainty, complexity, and ambiguity. The pace of change is accelerating, business and technology complexity is growing, and ... -
Improving the function and longevity of implantable drug and cell delivery devices by overcoming the foreign body response
(NUI Galway, 2023-02-23)The success of implantable medical devices is hindered by an inevitable inflammatory response called the Foreign Body Response. The human body recognises any implanted biomaterial as a foreign object, and isolates it ... -
Improving the sensitivity of radar-based breast imaging algorithms in diverse patient populations
(NUI Galway, 2018-09-03)Radar-based imaging is an emerging modality for breast cancer screening. Two commercial radar-based imaging devices are being tested in patient imaging studies. Promising initial results have highlighted the potential of ... -
In His Silvis Silere: The Monastic Site of Annegray - Studies in a Columbanian Landscape.
(2012-09-21)The monastic site of Annegray lies in the foothills of the Vosges Mountains in eastern France. Founded by the Irish saint, Columbanus, at some stage around 591A.D., it was the first of what was to become a group of three ... -
In silico bone tissue engineering - a multiscale and multiphysics approach
(2016-07-26)Mechanical stimulation in terms of fluid flow and mechanical strain can enhance the osteogenesis. Biomaterial scaffolds used in bone tissue engineering experiments have extremely complex geometry, which will result in the ... -
In the quest of the optimal collagen type II source for articular cartilage engineering
(NUI Galway, 2021-08-26)Articular cartilage is a specialised connective tissue of joints, which lacks blood vessels, lymphatics and nerves. The limited capability of articular cartilage to self-repair renders its regeneration a formidable challenge. ... -
In their own words. Factors impacting on the higher education (HE) experiences of black and minority ethnic (BME) students in Ireland
(NUI Galway, 2017-09-30)This study examines the experiences of black and minority ethnic (BME) groups in Irish higher education (HE). While the HE and wider experiences of this group are the focus of research and policy internationally, this study ... -
In vitro, pre-clinical and commercial evaluation of a novel xeno- and serum-free culture system for production of human bone marrow derived mesenchymal stem cells for bone regeneration
(2016-10-21)The therapeutic potential of mesenchymal stem cells (MSCs) is recognised in treating a wide range of debilitating diseases. For clinical-scale manufacturing, serum-free and xenogenic-free media formulations have been ...