Browsing University of Galway Theses by Subject "Specificity"
Now showing items 1-3 of 3
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Development and Application of a Computational Method for Determining the Specificity of Glycan-binding Proteins
(2013-09-25)Changes in cell-surface glycan patterns are markers for the presence of many different disease and cancer types, offering a relatively untapped niche for glycan-targeting reagents and therapeutics in diagnosis and treatment. ... -
Enzymes in the World of Computational Chemistry - Computational Studies on Structures, Dynamics, Mechanisms, and Specificity of Five Biologically Important Enzymes
(2012-10-30)The thesis demonstrates computational chemical methodology applied to some biologically important enzymes. Five enzymes have been studied, i.e. sortase A (SrtA), 2-Methyl-3-hydroxypyridine-5-carboxylic acid oxygenase ... -
Expression, purification and characterization of carbohydrate-binding proteins
(2014-05-29)Glycans play important roles in many biological interactions. They are involved in cell-cell interactions, function as a point of entry for viral infections and facilitate the adhesion of microbes in the body. Glycans of ...