Now showing items 1-5 of 5

  • Bayesian imputation of right censored data in time-to-event studies 

    Moghaddam, Shirin (NUI Galway, 2018-03-20)
    In time-to-event studies subjects are followed until the event of interest has happened. Subjects who do not experience the event are referred to as censored. Due to censoring, methods of plotting individual survival ...
  • Derivative Estimation in Noisy Data; an Additive Penalty P-Spline Approach 

    Simpkin, Andrew (2010-12-20)
    In many situations it is of primary interest to estimate the rate of change of the relationship between response and explanatory variables. In this thesis derivative estimation using spline smoothing is explored. A review ...
  • Extensions and Applications of Survival Trees in Medical Data 

    Alvarez-Iglesias, Alberto (2012-09-17)
    Survival trees are a non-parametric modeling strategy that can be included in the area of statistical modeling. These type of models can be used as an alternative to Cox proportional hazards models for the analysis of ...
  • Integration of Genetic Biomarkers in Prognostic Models for Breast Cancer Survival 

    Wall, Deirdre (2014-01-08)
    The main aim of my PhD is to create a prognostic model for invasive breast cancer patients for disease recurrence and death. The data were collected retrospectively and are comprised of 647 invasive breast cancer patients ...
  • Translational statistics and dynamic nomograms 

    Jalali, Amirhossein (NUI Galway, 2018-03-21)
    Translational Medicine, within biomedical and public health research domains, is defined as the convergence of basic and clinical research with the aim to transfer knowledge on the benefits and risks of therapies. The ...