Now showing items 1-5 of 5

  • Analysis of cytokine expression in breast cancer 

    Hartmann, Marion Charlotte (2014-10-29)
    Introduction: It has long been recognized that cancer develops in sites of chronic inflammation. Tumours seem to seize molecular pathways seen in wound healing and the inflammatory response and as a consequence appear as ...
  • Clinical Applications of Molecular Profiling in Colorectal Cancer 

    Kheirelseid, Elrasheid Ahmed Hassan (2011-06)
    Despite developments in diagnosis and treatment, 20% of colorectal cancer (CRC) patients present with metastatic disease and 30% of cases recur after curative surgery. Furthermore, the molecular factors involved in prognosis ...
  • Integration of Genetic Biomarkers in Prognostic Models for Breast Cancer Survival 

    Wall, Deirdre (2014-01-08)
    The main aim of my PhD is to create a prognostic model for invasive breast cancer patients for disease recurrence and death. The data were collected retrospectively and are comprised of 647 invasive breast cancer patients ...
  • Meseanchymal stem cell mediated sodium iodide symporter gene therapy of breast cancer 

    Ryan, James John (2014-05-07)
    Introduction: The Sodium Iodide Symporter (NIS) facilitates iodide accumulation in the thyroid and radioiodide imaging and treatment of thyroid disease. Studies have suggested that elevated levels of NIS expression in ...
  • MiRNAs as oncologic biomarkers for breast cancer 

    McDermott, Ailbhe (2014-08-18)
    Understanding of the molecular complexity underlying breast cancer has greatly advanced in recent years. Distinct phenotypic subtypes have been identified each of which carry prognostic and predictive implications. Despite ...