Browsing University of Galway Theses by Author "Laffey, John G."
Now showing items 1-4 of 4
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Enhancing the efficacy and therapeutic potential of human mesenchymal stromal cells (hMSCs) in clinically relevant sepsis models
González Esteban, Héctor (NUI Galway, 2022-08-30)Rationale: Sepsis is a systemic inflammatory process produced by the reaction of the immune system against a pathogen. This inflammatory process produces tissue damage leading into vital organ malfunction and, if not ... -
Evaluation of the efficacy of the Baska Mask
Alexiev, Vladimir (NUI Galway, 2018-03-22)The Baska mask is a new supraglottic airway device (SAD). Its novel features include a non-inflatable cuff consisting of a silicone membrane, and an oesophageal drainage system with sump reservoir, connected to 2 drainage ... -
Investigation of the therapeutic potential of mesenchymal stem/stromal cells in preclinical models of systemic sepsis
Keane, Colm (NUI Galway, 2020-10-29)Introduction: Sepsis is a syndrome of life-threatening physiologic, pathologic, and biochemical abnormalities resulting from infection 1. The host immune response, specifically the loss of immune homeostasis induced by ... -
Therapeutic potential of mesenchymal stromal cells in later phase antimicrobial resistant bacterial pneumosepsis: effects on the innate and adaptive immune system
Byrnes, Declan (NUI Galway, 2023-08-25)Introduction: Sepsis is a dysfunctional immune response to infection and remains a major source of mortality worldwide. Sepsis can be divided into three stages: early, transitionary, and late phase with the early phase ...