Browsing NUI Galway Theses by Subject "Centrosome; DNA damage response; Cell cycle; Checkpoint; Ionizing radiation; Cep135."
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(2011-12-16)The centrosome is the major microtubule organising center in animal cells. Following DNA damage, centrosome amplification can occur, which in turn can result in the formation of multipolar mitotic cells, and cell death. ...