Browsing University of Galway Theses by Subject "Cell therapy"
Now showing items 1-3 of 3
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Allogeneic cell therapy for osteoarthritis
(2016-05-11)Osteoarthritis is a debilitating multi-factorial joint disease which currently has no cure. Due to the significant immune cell mediated component in this disease a therapy which can modulate this inflammation and promote ... -
Development of next generation MSC therapeutics for critical limb ischaemia
(2015-02-19)Cell therapy with mesenchymal stem cells (MSCs) is being explored as a treatment for many ischaemic conditions of unmet medical need, such as critical limb ischaemia. MSC transplantation in humans has occurred in both ... -
Genetically modified mesenchymal stem cells overexpressing CCR2 for cell therapy in critical limb ischemia
(2017-09-21)Critical Limb Ischemia (CLI) is an advanced stage of Peripheral Arterial Disease (PAD) and a global health problem. Patients with CLI may present with rest pain, gangrene and/or ulceration of the lower limb. Effective ...