Browsing University of Galway Theses by Subject "Cancer Genomics"
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Analysis of clonal mutations in cancer as a means of studying variation in somatic mutation processes
(NUI Galway, 2023-09-13)Somatic mutations are mutations that arise throughout a person’s lifetime. They contribute to ageing, cancer and other age-related disorders. Recent technological advances led to many studies investigating somatic ... -
The role of genomic data in stratifying patients within predictive models for breast cancer survival outcome
(NUI Galway, 2024-04-15)Genomic instability (GI), defined as an increased tendency for genomic alterations to occur, is a common feature of cancers and is recognised as a “facilitating” hallmark of cancer. Genomic alterations include base ... -
Semantic knowledge graphs to understand tumor evolution and predict disease survival in cancer
(NUI Galway, 2020-07-06)Genomics technologies have generated large amounts of easily accessible biological -omics data, providing an unprecedented opportunity to study the mechanism in cancer. However, clinical research and the life sciences ...