Browsing University of Galway Theses by Author "Wu, Kevin Zhi Loong"
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Identification of IRS4 and TOP2A as novel CDC7 kinase interacting proteins
Wu, Kevin Zhi Loong (2016-02-08)CDC7 is an essential serine/threonine kinase required for the initiation of DNA replication in eukaryotic cells, through phosphorylating the MCM helicase complex. Formation of an active kinase requires the binding to ...