Browsing University of Galway Theses by Author "Woods, Robert J."
Now showing items 1-2 of 2
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Computationally Guided Directed Evolution of O-GlcNAcase into a Reagent Specific for [beta]-O-GlcNAc
Martin, Joanne C. (2013-12-13)Protein glycosylation with O-linked N-Acetylglucosamine (O-GlcNAc) is a post-translational modification of serine and threonine residues in nucleocytoplasmic proteins. Alterations in the glycosylation pattern of O-GlcNAc ... -
Development and Application of a Computational Method for Determining the Specificity of Glycan-binding Proteins
Grant, Oliver Colm (2013-09-25)Changes in cell-surface glycan patterns are markers for the presence of many different disease and cancer types, offering a relatively untapped niche for glycan-targeting reagents and therapeutics in diagnosis and treatment. ...