Browsing University of Galway Theses by Author "Lahue, Robert"
Now showing items 1-2 of 2
-
Molecular determinants of CTG.CAG repeat expansions in Huntington's disease
Keogh, Norma (2017-10)CTG•CAG repeat expansions are the underlying genetic cause for at least 12 inherited neurological disorders, including Huntington’s disease (HD) and myotonic dystrophy type I (DM1). Trinucleotide repeats (TNRs) are very ... -
Proteins that modulate trinucleotide repeat expansions in human cells
Frizzell, Aisling (2012-09-18)Expansions of trinucleotide repeats (TNRs) are the genetic cause of several inherited neurological diseases, such as Huntington's disease, myotonic dystrophy and fragile X syndrome. TNR diseases and their causal expansion ...