Browsing University of Galway Theses by Author "Keane, Lee-Ann"
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Small-molecule-based crosslinking and bioconjugation of biomolecules
Keane, Lee-Ann (NUI Galway, 2020-01-10)Chapter 1: The chemical modification and bioconjugation of proteins is an expanding yet challenging area of chemical biology. The superior nucleophilicity of cysteine presents it as a uniquely reactive bioconjugation handle. ...