Browsing University of Galway Theses by Author "Callagy, Grace"
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Characterisation of triple negative breast carcinoma and identification of the value of immunohistochemical markers and stromal tumour infiltrating lymphocytes
Shalaby, Aliaa Adel Salah-Eldin Mahmoud (NUI Galway, 2017-10)Breast cancer is a complex disease that encompasses multiple molecular subtypes that have different clinical behavior. The behavior can be influenced by both the characteristics of the cancer cells as well as the surrounding ... -
Identification of prognostic targets in breast cancer using immunohistochemical and in situ hybridisation methodologies
Ingoldsby, Helen Maria (2011-12-16)Advances in our understanding of the molecular mechanisms underlying breast cancer are leading to improvements in its management. Many of the recent gene-based signatures developed for breast cancer have highlighted the ... -
The prognostic value of protein and microRNA biomarkers in breast cancer and their role in tumour progression
Caffrey, Emer (2014-05-14)Identification of biomarkers has proven valuable in prognostication and treatment stratification of individual cases of breast cancer. microRNAs, short non-coding RNA molecules which negatively regulate translation of mRNA, ... -
Triple negative breast cancer: outcomes, subtypes and implications for treatment
Walsh, Elaine M. (NUI Galway, 2019-11-30)Triple negative breast cancer (TNBC) is a heterogeneous subtype representing 15-20% of all breast cancers and is associated with a poor prognosis, despite the advances made in other breast cancer subtypes. TNBC is defined ...