Browsing University of Galway Theses by Author "Breslin, Loretta"
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The primary cilium as a regulator of cellular senescence in human fibroblasts
Breslin, Loretta (2014-02-11)Somatic cells senesce in culture after a finite number of divisions, indefinitely arresting their proliferation. Among the major causes of senescence is persistent DNA damage signalling. DNA damage and senescence increase ...