Browsing University of Galway Theses by Title
Now showing items 939-958 of 2275
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The genomic architecture of nucleolar organiser regions on the short arms of human acrocentric chromosomes
(2015-09-29)Nucleolar Organiser Regions (NORs) are comprised of ribosomal gene (rDNA) arrays and adjacent sequences. Nucleoli, the sites of ribosome biogenesis and key regulators of cellular growth and proliferation, form around NORs. ... -
Genomic integrity of human norovirus and F-RNA bacteriophage as detected by RT-qPCR and its relationship to infectivity before and after UV-treatment
(NUI Galway, 2018-05-10)A long-range RT (loRT) qPCR assay described to estimate levels of infectious virus was identified in the literature and applied to human norovirus (HuNoV) genogroups I and II (GI and GII), and the surrogate virus F-RNA ... -
The genomics of soil-persistant E. coli
(NUI Galway, 2020-11-19)Escherichia coli’s remarkable ability to thrive both in the gut and in soil confounds many assumptions made about the bacterium’s ecological niche specialisation, and a growing body of research has challenged the long-held ... -
Genotype-dependent responsivity to inflammatory pain: the role of TRPV1 in the periaqueductal grey
(2016-09-21)The ability to experience pain is essential for survival, and to prevent potential tissue damage upon exposure to noxious stimuli. The periaqueductal grey - rostral ventromedial medulla – dorsal horn of the spinal cord ... -
Genus two Zhu theory for vertex operator algebras
(2014-06-30)In this thesis we consider the recursive properties of correlation functions for a vertex operator algebra on a genus two Riemann surface formed by sewing two tori together. We derive a system of formal recursive identities, ... -
Geomalacus maculosus: An assessment of trapping methods, forestry management impacts, and feeding preferences
(2017-02-24)The EU protected Lusitanian slug species Geomalacus maculosus Allman (Gastropoda: Arionidae) is found only in northern Iberia and the west of Ireland. Once thought to inhabit undisturbed habitats such as blanket bogs and ... -
Geometry effect in the fatigue behaviour of microscale 316L stainless steel specimens
(2012-06-07)Advances in engineering fabrication technology permit the manufacture of microscale components and devices. These tiny products are used in a wide range of applications, from medical devices to smart phones. There are ... -
Ghost Dances and Ring Shouts: Lakota and Gullah Nineteenth Century Musical Traditions in Comparative Perspective
(2014-03-04)During the nineteenth century, as the United States established itself as a nation and expanded its territory, the cultures of Native Americans and African Americans went through a period of profound change. The Lakota, a ... -
GIS-based advanced spatial analysis of total organic carbon and potentially toxic elements in European agricultural and Irish soils
(NUI Galway, 2022-03-01)With the increasing availability of data in environmental geochemistry, one of the biggest challenges is to extract useful knowledge and interpretable information from large and diverse data sources. The unprecedented ... -
Gliceas na teanga nach bhfuil láidir: Aistriúcháin liteartha ó Ghaeilge go Béarla, 1916-2016
(2017-06-10)Is í an téis atá á cur chun cinn sa tráchtas seo go raibh straitéis aistriúcháin chinnte ag na haistritheoirí liteartha a d’aistrigh saothair filíochta, ficsin agus neamhfhicsin, ó Ghaeilge go Béarla idir tús an fichiú ... -
A glyco approach for the treatment of Parkinson’s disease: From the glycobiological characterisation to the development of glyco-modulatory collagen-based hydrogel systems
(NUI Galway, 2021-12-20)Parkinson’s disease (PD) is the most common motor-related progressive neurodegenerative condition, mainly caused by the loss of dopaminergic neurons in the substantia nigra. Despite the increased knowledge regarding its ... -
Glycobiology of commensal bacteria with emphasis on cell surface adhesins and exopolysaccharides
(2014-09-25)The human gastro-intestinal tract (GIT) is an elaborate ecosystem specific to an individual and his physiological stage that involves inter- and intra-relationships between the bacteria composing the microbiota and between ... -
Glycoconjugates in Campylobacter jejuni-mediated disease
(2013-09-30)Gram-negative bacterium Campylobacter jejuni is a major cause of gastroenteritis in humans worldwide, and the most frequent infectious trigger in patients developing Guillain-Barré syndrome (GBS). While C. jejuni is ... -
Glycosaminoglycan Dependent Isolation of Mesenchymal Chondroprogenitor Populations from Human Bone Marrow
(2013-01-24)Osteoarthritis (OA) is a chronic disease of joints characterised by progressive destruction of articular cartilage resulting in painful, limited joint movement. Cartilage has a limited ability to self-repair due to low ... -
Glycosylation and glycoengineering of recombinant antibody fragments in Escherichia coli
(2016-11-14)Recombinant protein production (RPP) in Escherichia coli benefits from a long history of research which has facilitated the development of a plethora of strains and vectors suited to RPP applications. The identification ... -
Glycosylation in the injured and regenerating spinal cord, and the influence of biomaterial treatment
(NUI Galway, 2020-02-04)Traumatic spinal cord injury (SCI) results in disruption of tissue integrity leading to a loss of function. There has been minimal success in treating these injuries clinically, due to the inhibitory environment which ... -
The glycosylation signature of human urinary extracellular vesicles
(2015-12-22)Cells of virtually all organs and tissues are known to release large numbers of subcellular particles called extracellular vesicles (EVs) into bodily fluids such as blood and urine. There has been a growing interest in ... -
A godly Sybilla, an erudite wife and a burdensome sister: the formation and representation of women’s reputations within the Hartlib Circle 1641-1661
(NUI Galway, 2018-10-19)This thesis analyses the formation and representation of the reputations of three women: Katherine Jones, Viscountess Ranelagh (1615-1691); Dorothy Moore Dury (c.1612-1664); and Jean Appelius (fl.1638-1648), whose connection ... -
Golden cages: refugees, camps and the politics of law
(2015-12-09)This thesis explores the interplay between the refugee as a figure and the refugee camp as a space, and interrogates how this interplay has informed international refugee law as well as examining the gaps in international ... -
Governance, management control and social capital in mandated hospital networks
(NUI Galway, 2022-10-14)This study examines how mandated networks are governed and controlled by management. Mandated networks are the emergent product of reform implementation in the public sector in the expectation of greater efficiency and ...