Browsing University of Galway Theses by Title
Now showing items 933-952 of 2275
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Genetic determinants of disease characteristics of inflammatory bowel disease and diverticulitis
(2015-05-05)Background: Inflammatory Bowel Disease (IBD) is a complex, multigenic disease in which both the innate and adaptive immune systems play a strong role. Although over 40 microbes including bacteria, viruses and yeasts and ... -
Genetic diversity, evolutionary history and epigenetic analysis of East African highland bananas
(2015-05-13)Genetic variation describes naturally occurring genetic differences among individuals of the same species and permits flexibility and survival of a population in the face of changing environmental circumstances, diseases ... -
Genetically modified mesenchymal stem cells overexpressing CCR2 for cell therapy in critical limb ischemia
(2017-09-21)Critical Limb Ischemia (CLI) is an advanced stage of Peripheral Arterial Disease (PAD) and a global health problem. Patients with CLI may present with rest pain, gangrene and/or ulceration of the lower limb. Effective ... -
Genome dosage and parent of origin effects in a ploidy series of Arabidopsis thaliana
(2013-11-11)Polyploidy, the presence of more than two sets of chromosomes in an organism, plays major roles in plant evolution, development and function. Understanding the effects of polyploidization at the phenotypic and molecular ... -
Genome dosage, genetic hybridity and crop improvement
(NUI Galway, 2020-03-02)Plant breeding is focussed on introducing novel traits in plants, as well as enhancing or repressing traits already present. A noble objective in agriculture is to produce more food per unit area with overall fewer resources. ... -
Genomic and transcriptomic investigations into the feed efficiency phenotype of beef cattle
(NUI Galway, 2019-03-06)Improving the feed efficiency of cattle is a method to increase profits while simultaneously reducing the environmental impact of beef production. Residual feed intake (RFI) is a measure of feed efficiency, calculated as ... -
The genomic architecture of nucleolar organiser regions on the short arms of human acrocentric chromosomes
(2015-09-29)Nucleolar Organiser Regions (NORs) are comprised of ribosomal gene (rDNA) arrays and adjacent sequences. Nucleoli, the sites of ribosome biogenesis and key regulators of cellular growth and proliferation, form around NORs. ... -
Genomic integrity of human norovirus and F-RNA bacteriophage as detected by RT-qPCR and its relationship to infectivity before and after UV-treatment
(NUI Galway, 2018-05-10)A long-range RT (loRT) qPCR assay described to estimate levels of infectious virus was identified in the literature and applied to human norovirus (HuNoV) genogroups I and II (GI and GII), and the surrogate virus F-RNA ... -
The genomics of soil-persistant E. coli
(NUI Galway, 2020-11-19)Escherichia coli’s remarkable ability to thrive both in the gut and in soil confounds many assumptions made about the bacterium’s ecological niche specialisation, and a growing body of research has challenged the long-held ... -
Genotype-dependent responsivity to inflammatory pain: the role of TRPV1 in the periaqueductal grey
(2016-09-21)The ability to experience pain is essential for survival, and to prevent potential tissue damage upon exposure to noxious stimuli. The periaqueductal grey - rostral ventromedial medulla – dorsal horn of the spinal cord ... -
Genus two Zhu theory for vertex operator algebras
(2014-06-30)In this thesis we consider the recursive properties of correlation functions for a vertex operator algebra on a genus two Riemann surface formed by sewing two tori together. We derive a system of formal recursive identities, ... -
Geomalacus maculosus: An assessment of trapping methods, forestry management impacts, and feeding preferences
(2017-02-24)The EU protected Lusitanian slug species Geomalacus maculosus Allman (Gastropoda: Arionidae) is found only in northern Iberia and the west of Ireland. Once thought to inhabit undisturbed habitats such as blanket bogs and ... -
Geometry effect in the fatigue behaviour of microscale 316L stainless steel specimens
(2012-06-07)Advances in engineering fabrication technology permit the manufacture of microscale components and devices. These tiny products are used in a wide range of applications, from medical devices to smart phones. There are ... -
Ghost Dances and Ring Shouts: Lakota and Gullah Nineteenth Century Musical Traditions in Comparative Perspective
(2014-03-04)During the nineteenth century, as the United States established itself as a nation and expanded its territory, the cultures of Native Americans and African Americans went through a period of profound change. The Lakota, a ... -
GIS-based advanced spatial analysis of total organic carbon and potentially toxic elements in European agricultural and Irish soils
(NUI Galway, 2022-03-01)With the increasing availability of data in environmental geochemistry, one of the biggest challenges is to extract useful knowledge and interpretable information from large and diverse data sources. The unprecedented ... -
Gliceas na teanga nach bhfuil láidir: Aistriúcháin liteartha ó Ghaeilge go Béarla, 1916-2016
(2017-06-10)Is í an téis atá á cur chun cinn sa tráchtas seo go raibh straitéis aistriúcháin chinnte ag na haistritheoirí liteartha a d’aistrigh saothair filíochta, ficsin agus neamhfhicsin, ó Ghaeilge go Béarla idir tús an fichiú ... -
A glyco approach for the treatment of Parkinson’s disease: From the glycobiological characterisation to the development of glyco-modulatory collagen-based hydrogel systems
(NUI Galway, 2021-12-20)Parkinson’s disease (PD) is the most common motor-related progressive neurodegenerative condition, mainly caused by the loss of dopaminergic neurons in the substantia nigra. Despite the increased knowledge regarding its ... -
Glycobiology of commensal bacteria with emphasis on cell surface adhesins and exopolysaccharides
(2014-09-25)The human gastro-intestinal tract (GIT) is an elaborate ecosystem specific to an individual and his physiological stage that involves inter- and intra-relationships between the bacteria composing the microbiota and between ... -
Glycoconjugates in Campylobacter jejuni-mediated disease
(2013-09-30)Gram-negative bacterium Campylobacter jejuni is a major cause of gastroenteritis in humans worldwide, and the most frequent infectious trigger in patients developing Guillain-Barré syndrome (GBS). While C. jejuni is ... -
Glycosaminoglycan Dependent Isolation of Mesenchymal Chondroprogenitor Populations from Human Bone Marrow
(2013-01-24)Osteoarthritis (OA) is a chronic disease of joints characterised by progressive destruction of articular cartilage resulting in painful, limited joint movement. Cartilage has a limited ability to self-repair due to low ...