Browsing University of Galway Theses by Title
Now showing items 762-781 of 2267
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Examining the legitimation strategies of sustainability-oriented entrepreneurs
(NUI Galway, 2018-03-29)The idea that business plays a crucial role in the sustainable development of our world has grown within the corporate sustainability literature and in global sustainability discourse generally. There is also a growing ... -
Examining the role of a novel stromal cell protein CD362/Syndecan-2 in the breast tumour microenvironment.
(NUI Galway, 2019-09-04)Tumour-associated stromal cells play a key role in initiating and sustaining tumour growth, metastasis, immune control and chemo-resistance. Thus, identifying stromal proteins that contribute to carcinogenesis may open new ... -
Examining the role of trust in connecting management controls in big 4 audit firms
(NUI Galway, 2021-01-15)Connections exist between management control (MC) practices in organisations whereby different types of controls are loosely coupled or interdependent (act as complements or substitutes) (e.g., Grabner and Moers, 2013; ... -
Exchange in Chalcolithic and Early Bronze Age (EBA) Ireland: Connecting people, objects and ideas
(2014-12-01)The Chalcolithic and Early Bronze Age (EBA) in Ireland were periods of great flux, out of which and into which, novel technologies and institutions emerged and were transmitted. This thesis combines analysis of the material ... -
Exercises in style: A critical analysis of Dermot Healy’s stylistic development and a short story collection as a creative response
(NUI Galway, 2024-03-28)This practice-based research combines literary criticism and creative writing to explore how style reflects the writer’s evolving sensibilities. The academic research analyses the stylistic development of the prose of ... -
The Exhumation of Mass Graves by International Criminal Tribunals: Nuremberg, the former Yugoslavia and Rwanda
(2011-10-28)This thesis is a study on the practice of mass grave exhumation in the context of international criminal law, and more specifically as employed by international criminal tribunals. The primary institutions of focus are the ... -
Exosomal microRNAs in colorectal cancer
(2016)Cancer cells have been shown to release a variety of extracellular membrane vesicles including microvesicles known as exosomes. Exosomes have recently been found to contain microRNAs (miRNAs) however the full range within ... -
Exosome-encapsulated microRNAs as circulating biomarkers for breast cancer
(2016-06-15)Breast cancer is a heterogeneous group of diseases survival from which depends on stage at diagnosis. The development of blood-based biomarkers which may facilitate earlier detection and possibly subtype delineation remains ... -
Expansion and augmentation of social marketing theory and practice with systems science and mechanism, action, structure (MAS) theory to explore dynamic complexity and leverage points pertinent to the Galway cycling system
(NUI Galway, 2019-05-08)Social marketing is confronted by serious challenges of both endogenous and exogenous character. If these challenges are not properly addressed, social marketing risks entering into a deep, intrinsic and ontological crisis. ... -
The experience of providing care to those dying with dementia: family carers' perspectives
(NUI Galway, 2019-02-15)It is widely reported that carers who provide care for a family member with dementia endure physical and psychological burdens. Not only do they fulfil an important role for the person with dementia but also for the wider ... -
The experiences and implications of living with a BRCA1/2 alteration: Establishing the evidence base
(NUI Galway, 2023-03-23)Background BRCA1/2 alterations refer to a pathogenic variant in BRCA1 and BRCA2 genes. Having a BRCA1/2 alteration leads to a significant increase in lifetime risk of developing certain cancers, namely melanomas, ... -
Experimental and computational analysis of the mechanical behavior of poly(lactic-co-glycolic acid) during degradation for medical implant applications
(2016-01-25)Biodegradable polymers such as PLGA have been used in a wide range of biomedical applications due to their hydrolytic degradation and biocompatibility. The mechanical performance of biodegradable polymers during degradation ... -
Experimental and computational investigation into mechanobiology of osteocytes
(2014-10-31)Osteocytes are terminally differentiated bone cells, derived from osteoblasts, which comprise over 90% of the cells in mature bone tissue and are known to be highly sensitive to extracellular mechanical cues. The effect ... -
An experimental and computational investigation into procedural complications relating to transcatheter aortic heart valves
(NUI Galway, 2018-02-20)Although transcatheter aortic valves are widely used for treatment of high to medium risk patients with severe aortic stenosis, there are still many associated procedural complications. In particular, new on-set conductance ... -
Experimental and computational investigation of adhesion junction mechanosensation
(2017-02-28)Bone is an adaptive tissue that remodels in response to the mechanical loads placed upon it during normal daily activity. This remodelling process is vital to maintaining the mechanical integrity, mass and structure of ... -
Experimental and computational investigation of atherosclerotic plaque biomechanics
(NUI Galway, 2019-11-22)The overall objective of this thesis is to provide new insights into the composition and biomechanical behaviour of atherosclerotic plaque. Experimental and computational analysis techniques are developed to investigate ... -
Experimental and computational investigation of the active force generation of cells subjected to static and dynamic loading
(2016-05-13)The development of a mechanistic understanding of the processes by which cells sense and actively respond to the mechanical environment would represent a significant advance in the fields of biomechanics and tissue ... -
An experimental and computational investigation of the corrosion behaviour and mechanical performance of a bioabsorbable medical grade magnesium alloy
(NUI Galway, 2023-05-29)Magnesium-based medical implants have the potential to overcome several complications that arise with permanent metallic implants. Magnesium-based implants are biodegradable such that they can undergo absorption once ... -
An experimental and computational investigation of the high temperature behaviour of MarBN steel with application to effects of manufacturing
(NUI Galway, 2018-10-30)The key step for next generation power plants is the development of advanced materials capable of achieving high flexibility and efficiency at increased steam temperatures and pressures. Such operating conditions will cause ... -
Experimental and computational investigation of the impact of distorted stent expansion on the performance of transcatheter aortic valve replacements
(2014-12-22)Patients with calcific aortic valve stenosis present with calcium deposits on the aortic valve, which can result in non-circular and distorted expansion of self-expanding Transcatheter Aortic Valve Replacements. The effect ...