Browsing University of Galway Theses by Title
Now showing items 606-625 of 2232
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The effect of disinfectant exposure on Campylobacter spp. adaptation; A study on Campylobacter survival and on proteome and virulence genes expression
(2014-01-21)Campylobacter spp. are a common source of food contamination, especially in poultry products. To reduce the level of campylobacteriosis occurrence, different intervention strategies at poultry farms and processing plants ... -
Effect of glycaemic excursions on QT interval in diabetes patients
(NUI Galway, 2023-09-19)Glucose excursions in Diabetes Mellitus patients are associated with increased risk of cardiac morbidity and mortality (Kaul, Tarr, Ahmad, Kohner, & Chibber, 2013). With the evidence from several clinical trials, it ... -
The Effect of Pain on Cognitive Function: Preclinical and Clinical Investigations
(2012-10-19)Chronic pain is associated with high social and economic costs due to its disabling physical and psychological effects. Despite some evidence that chronic pain negatively affects cognitive function, little is known about ... -
Effect of spatial audio and movement control on user performance, awareness, and preference
(NUI Galway, 2021-09-27)More people are engaging with virtual environments recreationally and professionally. Game engines are more accessible, making it easier to craft virtual spaces, and home hardware improvements have made it accessible without ... -
The effectiveness of a structured educational reminiscence-based programme for staff in long-stay units on the quality of life of residents with dementia.
(2013-10-31)Background There is a growing appreciation of the potential use of psychosocial interventions in maintaining or improving the quality of life of people with dementia residing in long-stay care settings. Reminiscence is a ... -
The effectiveness of pilates in preventing falls in healthy older adults
(NUI Galway, 2021-08)Falls are a major cause of morbidity and mortality in older adults and evidence suggests that fall rates are rapidly increasing likely due to an aging population, which is placing a significant financial burden on health ... -
Effects of Acute Sleep Restriction on Laboratory and Ambulatory Physiological Reactivity in Young Adults
(2013-05-31)Introduction. Reduced sleep duration has been associated with adverse health outcomes, in particular negative cardiovascular health. The mechanisms by which sleep loss may influence cardiovascular health are unclear but ... -
The effects of anti-TNFα antibody therapy on peripheral blood mononuclear cells in patients with inflammatory bowel disease
(2015-09-30)Monocytes, recently classified as CD14++CD16- (classical), CD14++CD16+ (intermediate) and CD14dimCD16++ (non-classical) are considered to play a role in the pathogenesis of inflammatory bowel diseases (IBD). Anti-tumor ... -
The Effects of Biomedical Signal Compression in Wireless Ambulatory Healthcare
(2013-10-30)This thesis seeks to contribute to the field of ambulatory healthcare by examining methodologies to minimise the size of bioelectric signals, whilst preserving the quality of the diagnostic information contained within ... -
The Effects of Electron-Withdrawing Ring Substituents on the Reactivity of Cyclopentadienyl Ruthenium Complexes
(2011-09-09)This thesis describes the synthesis of ruthenium complexes which contain cyclopentadienyl ligands with electron-withdrawing ring substituents and the effects of these substituents on the reactivity of the metal centre. ... -
Effects of exogenous B-cell immunoglobulin binding protein (BIP) and BIP protein inducer X (BIX) on myelination
(NUI Galway, 2019-12-12)B-cell immunoglobulin binding protein (BiP) is an essential endoplasmic reticulum (ER) chaperone that belongs to the Hsp70 family, normally found in the ER lumen. However, BiP also has other extracellular and intracellular ... -
Effects of hypoxia on the response of the haematopoietic system to radiation-induced DNA damage
(2017-05-09)Preparative regimens using DNA damaging agents such as total body irradiation (TBI) prior to bone marrow transplantation (BMT) have profound deleterious effects on the hematopoietic system including the stromal cells that ... -
Effects of proteasome inhibition on cisplatin induced DNA damage responses in human cells
(2012-02-07)The proteasome is the main site of protein degradation in human cells, and plays a major role in the regulation of cellular processes including cell cycle progression, DNA repair and the DNA damage response. Proteasome ... -
Effects of remote ischaemic preconditioning on vascular and general surgery patients’ outcomes
(NUI Galway, 2017-09-29)Remote ischaemic preconditioning (RIPC) has been suggested as a non-invasive treatment option in many recent studies. The focus of this thesis is to evaluate the possible effect of this on major health problems in vascular ... -
The effects of Vibrio parahaemolyticus on Mitogen Activated Protein Kinase signalling pathways and intestinal epithelial host cell responses
(2013-02-20)Vibrio parahaemolyticus is a gram negative bacterium that is found in marine and estuarine environments. Although found amongst the commensal flora of shellfish, V. parahaemolyticus is a potent human pathogen. Consumption ... -
Efficient path query approaches over distributed linked data
(NUI Galway, 2021-03-18)In the past decade, graphs have become the defacto data model in some of the popular application domains such as bioinformatics, social, and road networks. One of the most used variants of the graph model is the labeled ... -
Elastin-based hydrogel as a treatment for critical limb ischemia, an insight into the glyco-host response
(NUI Galway, 2019-10-01)Critical limb ischemia (CLI) is severe impairment of the microcirculation resulting in inflammation, ischaemic pain, non-healing ulcers and gangrene. Over 20% of patients have no option but to undergo a major limb amputation. ... -
Elastin-like polypeptide mediated proangiogenic and anti-inflammatory gene therapy for critical limb ischemia
(2014-12-17)Critical limb ischemia is a major clinical problem. Despite rigorous treatment regimes, there has been modest success in reducing the rate of amputations in these patients. Reduced level of blood flow and enhanced inflammation ... -
Elastin-like recombinamers-based hydrogel modulates the post-ischemic remodelling in a clinically-relevant model of myocardial infarction
(NUI Galway, 2019-04-17)Myocardial infarction (MI) belongs to the family of cardiovascular diseases and represents the primary cause of worldwide mortality. Despite the promising results achieved in both small and large animal studies, recent ... -
Electrical impedance tomography for static lesion detection and identification in the brain
(NUI Galway, 2020-08-20)There is a clinical need for a novel approach to the detection of brain haemorrhage and clots. Such static lesions are characteristic of important conditions such as stroke, and traumatic brain injury. In these conditions ...