Browsing University of Galway Theses by Title
Now showing items 61-80 of 2267
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Analysing bovine sperm cells using flow cytometry
(NUI Galway, 2024-04-10)The accurate assessment of bull fertility is extremely important to the beef and dairy industry. In recent years, flow cytometry has become the dominant approach in sperm evaluation and is increasingly being used for quality ... -
Analysis and design of high frequency gapped transformers and planar transformers in LLC resonant converters
(2015-05-27)The LLC resonant converter is particularly applicable for power supplies applications since soft switching is easily achieved. The dual objectives in power supply are higher switching frequencies and higher power densities. ... -
Analysis and Implementation of Mixed-Mode Cohesive Zone Formulations for Cardiovascular Biomechanics Applications
(2013-02-18)A comprehensive theoretical analysis of potential-based and non-potential-based cohesive zone models (CZMs) under mixed-mode conditions is presented. Using the well established Xu-Needleman (XN) CZM, it is demonstrated ... -
Analysis and interpretation of epigenomic patterns in colonic epithelia
(2015-12-18)The methylation of cytosine nucleotides at the 5' position of DNA is a crucial epigenetic mechanism for the control of gene expression. Epigenome-wide associated studies have demonstrated that specific methylome patterns ... -
Analysis of clonal mutations in cancer as a means of studying variation in somatic mutation processes
(NUI Galway, 2023-09-13)Somatic mutations are mutations that arise throughout a person’s lifetime. They contribute to ageing, cancer and other age-related disorders. Recent technological advances led to many studies investigating somatic ... -
Analysis of cytokine expression in breast cancer
(2014-10-29)Introduction: It has long been recognized that cancer develops in sites of chronic inflammation. Tumours seem to seize molecular pathways seen in wound healing and the inflammatory response and as a consequence appear as ... -
Analysis of EMCCD gain estimation techniques for use in astronomical instruments
(NUI Galway, 2023-09-14)Electron-multiplied Charge Coupled Devices (EMCCDs) are used in many astro nomical instruments where they provide much improved signal to noise compared to conventional CCDs. However, the gain provided by electron-multiplication ... -
Analysis of gene regulation using high throughput genomics
(2012-10-23)The recent development of high-throughput genomics techniques and their subsequent applications have completely transformed the study of biology. The analysis, interpretation and storage of the resulting large volumes of ... -
Analysis of hepatic microRNA expression in postpartum dairy cows in negative energy balance
(2014-05-27)This thesis sets about to answer three research questions grounded in transcriptional regulation of hepatic genes in the high yielding postpartum dairy cow under negative energy balance (NEB). For this purpose we used ... -
Analysis of hepatic microRNA expression in postpartum dairy cows in negative energy balance
(2014-05-27)This thesis sets about to answer three research questions grounded in transcriptional regulation of hepatic genes in the high yielding postpartum dairy cow under negative energy balance (NEB). For this purpose we used ... -
An analysis of internal attacks on PTP-based time synchronization networks
(NUI Galway, 2021-12-21)The IEEE 1588 precision time protocol (PTP) is very important for many industrial sectors and applications that require time synchronization accuracy between computers down to microsecond and even nanosecond levels. ... -
Analysis of MiRNA Expression and Biomarker Potential in Common Diseases: Breast Cancer and Obesity
(2012-05-28)The two greatest health concerns worldwide at present are cancer and obesity; both of which continue to rise in incidence and are associated with high morbidity and mortality. Understanding the aetiology and mechanisms of ... -
Analysis of putative somatic mutations in 200,000 human exomes
(NUI Galway, 2023-09-19)Somatic mutations accumulate throughout life and contribute significantly to disease risk. While research into somatic mutation is well established in cancer, it is only in recent years that investigations into the ... -
Analysis of Saccharomyces cerevisiae Mec1 and Rad9 functions in the DNA Damage Response
(2012-10-01)The maintenance of genome integrity is critical for cell proliferation and survival of all organisms. Central to the DNA Damage Response are signal-transduction pathways, termed DNA damage checkpoints, conserved from ... -
Analysis of the behaviour of hybrid concrete lattice girder slabs during construction using laboratory and field testing
(NUI Galway, 2020-01-31)One of the emerging technologies in construction is the development of ‘smart structures’ which have sensors which will allow more efficient, resilient and sustainable structures to be designed and constructed. This research ... -
Analysis of the DNA damage response in model systems
(2014-07-24)The integrity of our DNA is constantly threatened by endogenous and exogenous sources of damage. In the absence of sufficient repair mechanisms, this damage can lead to mutations, potentially resulting in the development ... -
An analysis of the health risks associated with international travel
(2015-01-28)This thesis, submitted for the award of a doctoral degree in Medicine, represents an attempt to collate all of my original research projects in travel medicine completed at NUI Galway. Chapter 1 presents four projects ... -
Analysis of the mechanical performance of a biodegradable magnesium stent in a remodelling artery
(NUI Galway, 2018-09-28)Coronary stents made from degradable biomaterials such as magnesium alloy are an emerging technology in the treatment of coronary artery disease. Biodegradable stents provide mechanical support to the artery during the ... -
Analysis of the role of Rho GTPases in epithelial cells
(2014-11-19)Rho GTPases are a family of small GTP binding proteins that function as molecular switches for the control of a variety of fundamental cellular processes, and therefore represent potentially vital proteins for skin ... -
Analytical and Computational Methods for Analyzing Feedback Structure in System Dynamics Models
(2012-07-10)The system dynamics approach is based on the observation that dynamic behaviour arises as a result of endogenous interactions, particularly the interplay of various feedback loops. There are many open questions relating ...