Browsing University of Galway Theses by Title
Now showing items 415-434 of 2232
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Decoy Receptors block tumour cell eradication by TRAIL - Molecular engineering of TRAIL to evade decoy receptors
(2012-06-29)Tumour necrosis factor-related apoptosis inducing ligand (TRAIL) is a cytokine expressed by immune cells which selectively eradicates a wide range of cancer cells while leaving normal healthy cells unharmed. TRAIL binds ... -
Deep learning techniques in data augmentation and neural network design
(NUI Galway, 2020-05-22)In recent years, deep learning has revolutionized computer vision and has been applied to a range of problems where it often achieves accuracies equal to or greater than those obtainable by individual human experts. This ... -
Deep-retrofit decision-making support for achieving nearly zero-energy buildings with enhanced comfort
(NUI Galway, 2019-04-11)The emerging trends for deep-retrofit of existing buildings in Europe require formulation of strategies for nearly zero-energy buildings (nZEBs) and achieving benchmarks as outlined in the Energy Performance of Buildings ... -
Deepening democracy: Participation under international human rights law
(2017-09-30)This thesis examines the principle of participation, through which persons may have a direct role in decisions affecting them. This is said to be an integral principle of the international human rights framework, but thus ... -
Defining sense of community for public value creation in online public engagement
(NUI Galway, 2020-09-03)The potential of Web 2.0 technology to enable online public participation between government and the public has long held promise for governments, civic society and researchers. Public administrations have sought the ... -
The Dehumanisation Dynamic: A Criminology of Genocide
(2011-10-03)Why do individuals perpetrate the crime of genocide? This thesis utilises an interdisciplinary, criminological approach in order to explore this question. Interviews with perpetrators and victims of genocide in Rwanda, ... -
Denial of Wallet: Analysis of a looming threat and novel solution for mitigation using image classification
(NUI Galway, 2023-08-22)Serverless Computing is a powerful cloud-based architecture for the creation of applications. It boasts incredible scalability by running processes on a vast network of edge nodes. It decreases the time to deployment, ... -
Depth of field reduction for miniature-camera imaging
(NUI Galway, 2020-08-25)This thesis investigates the reduction of depth-of- field for miniature camera systems, such as the ones embedded in smartphones. The work on digital shallow depth-of- field is already mature and implemented in most modern ... -
Derivative Estimation in Noisy Data; an Additive Penalty P-Spline Approach
(2010-12-20)In many situations it is of primary interest to estimate the rate of change of the relationship between response and explanatory variables. In this thesis derivative estimation using spline smoothing is explored. A review ... -
Describing the indescribable: Lexical obscurity and biblical exegesis in early medieval Ireland
(NUI Galway, 2022-06-27)In the seventh century, medieval Irish scholars, who had received and internalised an educational system that placed the Bible at its very centre, began to produce texts that were marked by innovation in artistic style and ... -
Design and development of a performance evaluation framework for remote eye gaze estimation systems
(NUI Galway, 2019-04-02)In this dissertation, a comprehensive evaluation framework for remote eye gaze estimation systems that are implemented in consumer electronics applications is developed. For this, firstly, a detailed literature review ... -
Design and development of polymeric transfection vectors for gene delivery in Recessive Dystrophic Epidermolysis Bullosa
(2014-07-23)Recessive Dystrophic Epidermolysis Bullosa (RDEB) is caused by mutations in the collagen VII gene (COL7A1) that lead to an alteration of function or a reduction in the amounts of collagen VII protein (C7). Any of these ... -
Design and development of smart contract system for blockchain based applications
(NUI Galway, 2021-05-17)The work presented in this thesis describes the design and development of smart contract system for blockchain based applications. The main objective is to investigate the current state of blockchain technology and its ... -
Design and evaluation of an automated algorithm for cardiac risk stratification
(2013-12-20)In the United States, sudden cardiac death (SCD) claims approximately 450,000 lives each year, more lives than stroke, lung and breast cancer and AIDS combined. In the United Kingdom and Ireland, the combined figure is ... -
The Design and Evaluation of Graphical Radial Menus
(2011-12-05)Graphical menus provide slow performance and yet users often try to select menu commands as fast as possible. Shortcut techniques that enable users to by-pass selections from a graphical menu are fast, but are not the ... -
Design and synthesis of biocompatible metal-organic frameworks for anti-cancer, anti-tubercular and MRI application
(NUI Galway, 2023-07-11)Metal-organic frameworks (MOFs) are relatively new porous materials that have attracted significant attention in recent decades. Potential applications in gas storage and separation have been at the forefront of this ... -
Design and synthesis of macrocycles, peptides and coiled coils with sugar connections
(2016-06-09)Migrastatin is a secondary metabolite that is formed from the bacterium Streptomyces platensis. This compound has shown promising anti-metastatic activity by inhibiting tumour cell migration. Published derivatives of this ... -
Design and synthesis of novel constrained glycomimetics as inhibitors of galectins and galactosidases
(NUI Galway, 2023-10-10)Chapter 1 gives a brief introduction to carbohydrate structure, discussing factors influencing reactivity and conformation, such as the anomeric and exo-anomeric effect. Chapter 1 mentions methods of structural analysis ... -
Design Exploration of EMBRACE Hardware Spiking Neural Network Architecture and Applications
(2014-02-05)The operation and structure of the human brain has inspired the development of next generation smart embedded computing systems. The cognitive abilities of the human brain have been partially explained by the dense and ... -
Design of fibre-reinforced polymer composite blades for wind and tidal turbines
(2017-09)There is substantial opportunity in the development of wind and tidal current turbines to help decarbonise national energy systems and to expand the economic potential of the European Union. However, well-documented cases ...