Browsing University of Galway Theses by Title
Now showing items 239-258 of 2236
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Centromere function in asymmetrically dividing Drosophila germline stem cells
(NUI Galway, 2023-03-28)Germline stem cells (GSCs) undergo asymmetric cell division (ACD) to give rise to one stem cell residing in the niche and one differentiating daughter cell. The daughter cell subsequently divides through mitosis and meiosis ... -
Centrosome cohesion: functions of C-NAP1
(2016-01-07)Double stranded DNA encodes the genetic material of the cell. Replication and segregation cycles are regulated in order to maintain the integrity of the DNA sequence from one cell cycle to the next. Detection of lesions ... -
Cerebral palsy in the West of Ireland and the application of the international criteria for the identification of acute intrapartum hypoxia: a cohort study.
(2012-05-09)Abstract Background Cerebral palsy is one of the most severe disabilities in childhood and occurs in 1-3 per 1,000 live births in Europe. This epidemiological study looked at a cohort of children with cerebral palsy to ... -
Cervical lymphadenopathy in lung cancer
(NUI Galway, 2021-09-18)Overall, in the thesis we showed that cervical lymphadenopathy is frequently present in patients with lung cancer and mediastinal lymphadenopathy on CT to a degree that justifies screening for it routinely. We have shown ... -
‘Cé leis í?’ Determining the legal position of the ‘Surrogate’ in a surrogacy relationship through the Reproductive Justice Framework: A proposed model for Ireland.
(NUI Galway, 2019-05-29)This thesis asks the question: Cé leis í? (Who is she?) This question refers to the uniquely Irish kinship structure which recognises complex filiation structures. Similarly, advances in assisted human reproduction which ... -
Chain transfer to solvent in the radical polymerization of acrylamide monomers, controlled/living radical polymerizations, including in supercritical carbon dioxide and preparation of carbon dioxide responsive micelles
(2014-12-11)Chapter 1 provides a general introduction to radical polymerization, including chain transfer, and controlled/living radical polymerization. A review of the literature since 2009 on heterogeneous controlled/living radical ... -
Challenging assumptions of vulnerability: the significance of gender in the work, lives and identities of women human rights defenders
(2018-02-16)In 1998, the United Nations General Assembly adopted the Declaration on the Right and Responsibility of Individuals, Groups and Organs of Society to Promote and Protect Universally Recognised Human Rights and Fundamental ... -
Changes in alcohol-related cognitions and drinking behaviours from early to mid-adolescence: A longitudinal mixed methods study
(NUI Galway, 2022-03-21)Alcohol use, during early adolescence specifically, has been associated with a range of negative health and social consequences. While the prevalence of adolescent drinking behaviours has decreased in recent decades, there ... -
Changes in anthropometric and metabolic outcomes during and after a milk-based meal replacement programme in bariatric patients
(NUI Galway, 2020-04-14)During this work, I examined a cohort of patients with severe and complicated obesity undergoing a milk-based intensive weight management programme, examining changes in various traits in the short and medium term. Firstly, ... -
Changing diet and physical activity behaviour in type 2 diabetes
(NUI Galway, 2022-03-14)The aim of this thesis was to design an artefact to support diet and physical activity behaviour change in people with type 2 diabetes. The first step was to identify behaviour change techniques (BCTs) in diet and physical ... -
Characterisation and analysis of Memory T-cells in COVID-19 patient sample
(NUI Galway, 2023-08-08)Background: Immunological memory is the key to long-term protection against disease. It is the hallmark of adaptive immunity which facilitates an accelerated and enhanced immune response against a pathogen encountered ... -
Characterisation and testing of carbon fibre PEEK for linerless composite cryogenic storage tanks
(NUI Galway, 2020-05-07)Cryogenic storage tanks, also known ’cryotanks’, are an important component of space launch vehicles. Cryotanks can form an integral part of the overall structure of the launch vehicle and also represent a significant ... -
Characterisation of bovine pericardium and alternative treatments for its application as biomaterial
(NUI Galway, 2020-04-09)Bovine pericardium is an extensively used biomaterial utilised in a wide range of biomedical devices such as bioprosthetic heart valves. The characterisation techniques employed for the analysis of bovine pericardium and ... -
Characterisation of core histone sequences and nuclear mobility using a reproducible research approach
(2017-09-19)Chromatin is a dynamic complex that controls access to genetic information by undergoing structural reconfigurations. Understanding this dynamic can provide insights into the biological implications of chromatin ... -
Characterisation of histone variants in the cnidarian Hydractinia
(NUI Galway, 2019-02-21)Hydractinia is a marine hydrozoan cnidarian that has been a model organism for developmental biology for over a century. Very few studies have been carried out on chromatin biology in cnidarians. To date, there is no ... -
Characterisation of human nucleolar organisers located in previously uncharted regions of the human genome
(NUI Galway, 2019-01-18)The nucleolus is a large, sub-nuclear domain and the site of ribosome biogenesis. Nucleoli form around chromosomal loci called ‘nucleolar organiser regions (NORs) located on the short arms of the human acrocentric ... -
Characterisation of novel ATM-interacting factors involved in double-strand break repair
(2012-10-22)Ataxia-telangiectasia (A-T) is a rare human disease characterized by cerebellar degeneration, immune system defects and cancer predisposition. The disease has been the subject of intense scientific scrutiny, particularly ... -
Characterisation of novel Histone H3 RAD9 mutants defective in the DNA damage response in Saccharomyces cerevisiae
(2013-02-28)The DNA damage response (DDR) is a signal transduction cascade, which regulates cell cycle progression, gene transcription and DNA repair. Histones also play a vital role in the activation of the DDR and have been shown ... -
Characterisation of rotationally moulded polymer liners for low permeability cryogenic applications in composite overwrapped pressure vessels
(2016-09-20)Composite overwrapped pressure vessels (COPVs) have become a critical component in satellite and space applications due to their ability to store highly permeating fuels at high pressures and under cryogenic conditions. ... -
Characterisation of sex differences in behavioural domains and antidepressant response in two rat models of depression
(NUI Galway, 2018-10-17)Although the rate of depression is known to be almost twice as high in women compared to men, most evaluation of antidepressant efficacy involved only males until the early 1990s. In pre-clinical depression research male ...