Browsing University of Galway Theses by Title
Now showing items 1366-1385 of 2273
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Medical student selection: a mixed methods study
(2015-09-29)Selection to medicine is widely considered the single most important assessment of a doctor's medical career. It is a key deciding factor in the composition of the medical workforce. Selectors have a social responsibility ... -
Medicalisation in Ireland - A mixed methods analysis using the case of statins for primary prevention of cardiovascular disease
(NUI Galway, 2019-05-29)Statins are a class of drugs that lower blood cholesterol levels and were originally used to prevent further recurrences in those with a history of cardiovascular disease (CVD). Over time, their use has been extended to ... -
Medication adherence among people living with multimorbidity: prevalence, predictors and intervention options
(NUI Galway, 2023-01-10)Background. Multimorbidity refers to the presence of multiple chronic conditions in an individual person. The prevalence of multimorbidity is increasing globally, presenting a significant challenge for healthcare systems ... -
Medication adherence in resistant hypertension: An investigation of prevalence, psychological predictors and patient perspectives
(NUI Galway, 2018-09-28)Background: Resistant hypertension is a chronic condition in which the arterial blood pressure remains persistently above goal despite concurrent treatment with three or more antihypertensive agents of different classes. ... -
Medieval settlement enclosures and resource management of living trees in Gaelic Ireland
(NUI Galway, 2019-08-23)The aim of this thesis is to problematise and investigate relationships between living trees and earthen settlement enclosures, mainly termed ráth and commonly used by Gaelic society in medieval Ireland (c. 8th – 17th ... -
Mental health First Aid in an Irish Context
(2013-02-01)Mental Health First Aid (MHFA) is an early intervention training course designed to improve the knowledge, skills and confidence of non-clinicians to manage mental health emergencies. The course aims to minimise the ... -
Meseanchymal stem cell mediated sodium iodide symporter gene therapy of breast cancer
(2014-05-07)Introduction: The Sodium Iodide Symporter (NIS) facilitates iodide accumulation in the thyroid and radioiodide imaging and treatment of thyroid disease. Studies have suggested that elevated levels of NIS expression in ... -
Mesenchymal stem cell mediated delivery of Extracellular Vesicle (EV)-encapsulated microRNAs for the treatment of breast cancer
(NUI Galway, 2020-08-04)Mesenchymal Stem Cells (MSCs) hold the ability to home to the site of the tumour and bypass the host immune system. Extracellular Vesicles (EVs) are thought to be a fingerprint of the parent cell and therefore MSC-EVs ... -
Mesenchymal stem cells for therapeutic application in corneal transplantation
(2014-02-12)Although corneal transplantation success rates are high within the first year, the prognosis is much less favourable 5 years post-transplantation with immune-mediated rejection the primary cause of allograft failure. For ... -
Mesenchymal stromal cells: their immunosuppressive capacity and protein production profile
(2016-08)The clinical benefits of mesenchymal stromal cell (MSC) based therapies for immune disorders and degenerative diseases are based on their combined ability to modulate the immune system and to differentiate into different ... -
Metal removal and recovery from zinc refinery residue using microbiologically produced elemental chalcogen nanoparticles
(NUI Galway, 2022-09-20)This research aimed at investigating the application of elemental chalcogen nanoparticles for the removal of metals from wastewaters. In the first part of the study, biogenic (Bio) selenium nanoparticles (SeNPs) were ... -
Metal-based dithiocarbamato glycoconjugates: a suitable strategy to target tumour glycolysis?
(NUI Galway, 2019-03-11)Rapidly dividing tumour cells require higher amounts of nutrients and energy for their fast proliferation, and glucose is no exception (the so-called “Warburg effect”). Consequently, such increased demand of glucose by ... -
Metal-based glycoconjugates as molecular sensors for lectins and anti-adhesives
(NUI Galway, 2024-04-05)The anti-microbial resistance crisis has been inexorably developing at ever more alarming levels in the 21st century. The WHO regularly updates a list of bacterial and fungal critical priority pathogens for which new ... -
Metal-based glycoconjugates for the targeted anticancer chemotherapy
(NUI Galway, 2023-08-30)Rapidly dividing tumor cells require higher amounts of nutrients and energy to sustain their abnormal proliferation rates, and glucose is no exception. Glucose enters the cell by facilitated diffusion through the glucose ... -
Metal-based theranostic and therapeutic agents for the targeted treatment and imaging of tumors
(NUI Galway, 2024-01-12)The present PhD thesis resulted from the undertaking of two separate research projects, both anyway being strictly related to the rational design of metal complexes with potential therapeutic and/or diagnostic ... -
Metaphor processing in tweets
(NUI Galway, 2021-03-15)Metaphor plays an important role in defining the interplay between cognition and language. Despite its fuzziness, this ubiquitous figurative device is an essential element of human communication that allows us (as humans) ... -
Metastatic breast cancer: Patterns of metastasis and novel biomarkers
(NUI Galway, 2018-05-25)Breast cancer is a heterogeneous disease and is the leading cause of cancer-related deaths among women, with metastatic disease the principle cause of mortality. In recent years great advances have been made in stratifying ... -
Methamphetamine exposure during pregnancy: Neurodevelopmental consequences for the offspring
(2016-04-05)Methamphetamine (MA) abuse during pregnancy is a significant concern worldwide. Improving our understanding of the consequences of such exposure on the child is paramount and animal models provide an alternative method of ... -
Methods for defining dynamic online communities and community detection in fast-paced social media streams
(NUI Galway, 2019-05-02)Microblogging social media focuses on fast open real-time communication using short messages between users and their followers. Twitter is currently one of the largest and widely known microblogging OSN in the world, with ...