Browsing School of Natural Sciences by Subject "DNA damage response"
Now showing items 1-2 of 2
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Cell cycle-dependent formation of Cdc45-Claspin complexes in human cells is compromized by UV-mediated DNA damage
(Wiley, 2013-08-02)The replication factor Cdc45 has essential functions in the initiation and elongation steps of eukaryotic DNA replication and plays an important role in the intra-S-phase checkpoint. Its interactions with other replication ... -
Mrc1, Tof1 and Csm3 inhibit CAG·CTG repeat instability by at least two mechanisms
(Springer, 2008)Trinucleotide repeats frequently expand and contract in humans and model organisms. Protein factors that modulate this process have been found by candidate gene approaches or mutant screens for increased expansion ...