Browsing School of Natural Sciences by Author "|~|1267880|~|"
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Comparative genome analysis identifies novel nucleic acid diagnostic targets for use in the specific detection of Haemophilus influenzae
Coughlan, Helena; Reddington, Kate; Tuite, Nina; Wee Boo, Teck; Cormican, Martin; Barrett, Louise; Smith, Terry; Clancy, Eoin; Barry, Thomas (Elsevier, 2015-06-23)Haemophilus influenzae is recognised as an important human pathogen associated with invasive infections, including bloodstream infection and meningitis. Currently used molecular-based diagnostic assays lack specificity in ... -
Cross platform standardisation of an experimental pipeline for use in the identification of dysregulated human circulating MiRNAs
Kelly, Helena; Downing, Tim; Tuite, Nina; Smith, Terry; Kerin, Michael; Dwyer, Róisín M.; Clancy, Eoin; Reddington, Kate; Barry, Thomas (Public Library of Science, 2015-09-10)Micro RNAs (miRNAs) are a class of highly conserved small non-coding RNAs that play an important part in the post-transcriptional regulation of gene expression. A substantial number of miRNAs have been proposed as biomarkers ... -
Determination of survival of wildtype and mutant Escherichia coli in soil
Somorin, Yinka; O'Byrne, Conor (Bio-protocol, 2017-07-20)E. coli resides in the gastrointestinal tract of humans and other warm-blooded animals but recent studies have shown that E. coli can persist and grow in various external environments including soil. The general stress ... -
Identifying the sources and sinks of CDOM/FDOM across the Mauritanian Shelf and their potential role in the decomposition of superoxide (O2- )
Heller, Maija I.; Wuttig, Kathrin; Croot, Peter L. (Frontiers Media, 2016-08-03)Superoxide (O−2O2-) is a short lived reactive oxygen species (ROS) formed in seawater by photochemical or biological sources, it is important in the redox cycling of trace elements and organic matter in the ocean. The ... -
Pollination ecology of Desmodium setigerum (Fabaceae) in Uganda; do big bees do it better?
Stanley, Dara; Otieno, Mark; Syeijven, Karin; Berlin, Emma Sandler; Piironen, Tiina; Willmer, Pat; Nuttman, Clive (2016-09)Explosive pollen release is documented in many plant families, including the Fabaceae. Desmodium setigerum E. Mey (Fabaceae) is a perennial herb with single trip explosive pollen release found in eastern Africa, and the ... -
A rapid culture independent methodology to quantitatively detect and identify common human bacterial pathogens associated with contaminated high purity water
Minogue, Elizabeth; Tuite, Nina; Smith, Cindy J.; Reddington, Kate; Barry, Thomas (BioMed Central, 2015-02-18)Water and High Purity Water (HPW) distribution systems can be contaminated with human pathogenic microorganisms. This biocontamination may pose a risk to human health as HPW is commonly used in the industrial, pharmaceutical ...