Browsing School of Natural Sciences by Title
Now showing items 1-20 of 63
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Adenylate cyclase toxin from Bordetella pertussis synergizes with lipopolysaccharide to promote innate interleukin-10 production and enhances the induction of Th2 and regulatory T cells
(American Society for Microbiology, 2004-03)Adenylate cyclase toxin (CyaA) from Bordetella pertussis can subvert host immune responses allowing bacterial colonization. Here we have examined its adjuvant and immunomodulatory properties and the possible contribution ... -
An assessment of RNA content in Prymnesium parvum, Prymnesium polylepis, cf. Chattonella sp. and Karlodinium veneficum under varying environmental conditions for calibrating an RNA microarray for species detection
(Wiley, 2014-02-03)Traditional methods of identification and enumeration can be somewhat ambiguous when identifying phytoplankton that requires electron microscopic examination to verify specific morphological features. Members of the genus ... -
Bcl-2 family on guard at the ER
(American Physiological Society, 2009)The endoplasmic reticulum (ER) is the main site for protein folding, lipid biosynthesis and calcium storage in the cell. Disturbances of these critical cellular functions lead to ER stress. The ER responds to disturbances ... -
Beyond the green: understanding the evolutionary puzzle of plant and algal cell walls
(American Society of Plant Biologists, 2010-04-26)Niklas (2000) defined plants as “photosynthetic eukaryotes,” thereby including brown, red, and green macroalgae and microalgae. These groups share several features, including the presence of a complex, dynamic, and ... -
Bioinformatic identification and analysis of extensins in the plant kingdom
(Public Library of Science, 2016-02-26)Extensins (EXTs) are a family of plant cell wall hydroxyproline-rich glycoproteins (HRGPs) that are implicated to play important roles in plant growth, development, and defense. Structurally, EXTs are characterized by the ... -
Bordetella pertussis expresses a functional type III secretion system that subverts protective innate and adaptive immune responses
(American Society for Microbiology, 2008-01)Certain bacteria use a type III secretion system (TTSS) to deliver effector proteins that interfere with cell function into host cells. While transcription of genes encoding TTSS components has been demonstrated, studies ... -
Bumblebee learning and memory is impaired by chronic exposure to a neonicotinoid pesticide.
(Nature Publishing Group, 2015-11-16)Bumblebees are exposed to pesticides applied for crop protection while foraging on treated plants, with increasing evidence suggesting that this sublethal exposure has implications for pollinator declines. The challenges ... -
Cell wall evolution and diversity
(Frontiers Media, 2012-07-06)Plant cell walls display a considerable degree of diversity in their compositions and molecular architectures. In some cases the functional significance of a particular cell wall type appears to be easy to discern: secondary ... -
The cell walls of pteridophytes and other green plants - a review
(British Pteridological Society, 2006-12-22)The cell wall is one of the defining characteristics of plants and is a fundamental component in normal growth and development. Cell wall composition is a potentially valuable source of phylogenetic information as notable ... -
Ceratopteris richardii (C-Fern): a model for investigating adaptive modification of vascular plant cell walls
(Frontiers Media, 2013-09-23)Plant cell walls are essential for most aspects of plant growth, development, and survival, including cell division, expansive cell growth, cell-cell communication, biomechanical properties, and stress responses. Therefore, ... -
Charophytes: evolutionary giants and emerging model organisms
(Frontiers Media, 2016-10-10)Charophytes are the group of green algae whose ancestral lineage gave rise to land plants in what resulted in a profoundly transformative event in the natural history of the planet. Extant charophytes exhibit many features ... -
Comparative genome analysis identifies novel nucleic acid diagnostic targets for use in the specific detection of Haemophilus influenzae
(Elsevier, 2015-06-23)Haemophilus influenzae is recognised as an important human pathogen associated with invasive infections, including bloodstream infection and meningitis. Currently used molecular-based diagnostic assays lack specificity in ... -
Comparison of established diagnostic methodologies and a novel bacterial smpB real-time PCR assay for the specific detection of haemophilus influenzae associated with respiratory tract infections
(American Society for Microbiology, 2015-06-23)Haemophilus influenzae is a significant causative agent of respiratory tract infections (RTI) worldwide. The development of a rapid H. influenzae diagnostic assay that would allow for the implementation of infection control ... -
Competition between the Yops of Yersinia enterocolitica for delivery into eukaryotic cells: Role of the SycE chaperone binding domain of YopE
(American Society for Microbiology, 2000-09)A type III secretion-translocation system allows Yersinia adhering at the surface of animal cells to deliver a cocktail of effector Yops (YopH, -O, -P, -E, -M, and -T) into the cytosol of these cells. Residues or codons 1 ... -
Contrasting responses to nutrient enrichment of prokaryotic communities collected from deep sea sites in the Southern Ocean
(MDPI Open-Access Journals, 2013-09-13)Abstract: Deep water samples (ca. 4,200 m) were taken from two hydrologically-similar sites around the Crozet islands with highly contrasting surface water productivities. Site M5 was characteristic of high productivity ... -
Control of transfer and weak closure in fusion systems
(2010)We show that K¿ and K¿ control transfer in every fusion system on a finite p-group when p ¿ 5, and that they control weak closure of elements in every fusion system on a finite p-group when p ¿ 3. This generalizes resultsof ... -
Cross platform standardisation of an experimental pipeline for use in the identification of dysregulated human circulating MiRNAs
(Public Library of Science, 2015-09-10)Micro RNAs (miRNAs) are a class of highly conserved small non-coding RNAs that play an important part in the post-transcriptional regulation of gene expression. A substantial number of miRNAs have been proposed as biomarkers ... -
Ecological variation in response to mass-flowering oilseed rape and surrounding landscape composition by members of a cryptic bumblebee complex
(Public Library of Science, 2013-06-19)The Bombus sensu stricto species complex is a widespread group of cryptic bumblebee species which are important pollinators of many crops and wild plants. These cryptic species have, until now, largely been grouped together ... -
Engineering recombinant antibodies for polymer biofunctionalization
(Wiley, 2015-08-18)The attachment of recognition elements such as antibody fragments to polymeric substrates can be used to mediate cell- or protein-specific interactions. In this work, single-chain Fv (scFv) antibody fragments were isolated ... -
Expansions of CAG·CTG repeats in immortalized human astrocytes.
(Oxford University Press, 2007)Expansions of trinucleotide repeats (TNRs) are the genetic cause for a number of neurodegenerative disorders. In some of these diseases, ongoing somatic expansions in the brain are thought to contribute to disease progression. ...