Browsing School of Natural Sciences by Author "http://dx.doi.org/10.13039/501100001588"
Now showing items 1-4 of 4
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Generation of a panel of high affinity antibodies and development of a biosensor-based immunoassay for the detection of okadaic acid in shellfish
Le Berre, Marie; Kilcoyne, Michelle; Kane, Marian (Elsevier, 2015-07-10)Okadaic acid (OA) and its derivatives, DTX-1 and DTX-2, are marine biotoxins associated with diarrhetic shellfish poisoning. Routine monitoring of these toxins relies on the mouse bioassay. However, due to the technical ... -
Impact of trichloroethylene exposure on the microbial diversity and protein expression in anaerobic granular biomass at 37°C and 15°C
Siggins, Alma; Enright, Anne-Marie; Abram, Florence; Botting, Catherine; O'Flaherty, Vincent (Hindawi Publishing Corporation, 2012-09-14)Granular biomass from a laboratory-scale anaerobic bioreactor trial was analysed to identify changes in microbial community structure and function in response to temperature and trichloroethylene (TCE). Two bioreactors ... -
In vitro comparative cytotoxicity study of a novel biocidal iodo-thiocyanate complex
Tonoyan, Lilit; Boyd, Aoife; Fleming, Gerard T.A.; Friel, Ruairi; Gately, Carol M.; Mc Cay, Paul H.; O'Flaherty, Vincent (Elsevier, 2018-04-03)Novel biocides, which avoid the induction of cross-resistance to antibiotics, are an urgent societal requirement. Here, we compared the cytotoxic and bactericidal effects of a new antimicrobial agent, the iodo-thiocyanate ... -
RIP2 enhances cell survival by activation of NF-ĸB in triple negative breast cancer cells
Jaafar, Rola; Mnich, Katarzyna; Dolan, Sarah; Hillis, Jennifer; Almanza, Aitor; Logue, Susan E.; Samali, Afshin; Gorman, Adrienne M. (Elsevier, 2018-02-06)Receptor-interacting protein 2 (RIP2) is an essential mediator of inflammation and innate immunity, but little is known about its role outside the immune system. Recently, RIP2 has been linked to chemoresistance of triple ...