Browsing College of Science by Author "Dwyer, Róisín M."
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Characterization of nanosensitive multifractality in submicron scale tissue morphology and its alteration in tumor progression
Das, Nandan; Alexandrov, Sergey; Gilligan, Katie E.; Dwyer, Róisín M.; Saager, Rolf B.; Ghosh, Nirmalya; Leahy, Martin (Society of Photo-optical Instrumentation Engineers, 2021-01-11)Significance: Assessment of disease using optical coherence tomography is an actively investigated problem, owing to many unresolved challenges in early disease detection, diagnosis, and treatment response monitoring. The ... -
Cross platform standardisation of an experimental pipeline for use in the identification of dysregulated human circulating MiRNAs
Kelly, Helena; Downing, Tim; Tuite, Nina; Smith, Terry; Kerin, Michael; Dwyer, Róisín M.; Clancy, Eoin; Reddington, Kate; Barry, Thomas (Public Library of Science, 2015-09-10)Micro RNAs (miRNAs) are a class of highly conserved small non-coding RNAs that play an important part in the post-transcriptional regulation of gene expression. A substantial number of miRNAs have been proposed as biomarkers ... -
Nanoscale structure detection and monitoring of tumour growth with optical coherence tomography
Das, Nandan; Sergey, Alexandrov; Zhou, Yi; Gilligan, Katie E.; Dwyer, Róisín M.; Leahy, Martin (Royal Society of Chemistry, 2020-05-25)Approximately 90% of cancers originate in epithelial tissues leading to epithelial thickening, but the ultrastructural changes and underlying architecture are less well known. Depth resolved label free visualization of ...