Browsing College of Science by Author "Santocanale, Corrado"
Now showing items 1-3 of 3
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Cell cycle-dependent formation of Cdc45-Claspin complexes in human cells is compromized by UV-mediated DNA damage
Broderick, Ronan; Rainey, Michael D.; Santocanale, Corrado; Nasheuer, Heinz-Peter (Wiley, 2013-08-02)The replication factor Cdc45 has essential functions in the initiation and elongation steps of eukaryotic DNA replication and plays an important role in the intra-S-phase checkpoint. Its interactions with other replication ... -
Synthesis of migrastatin analogues as inhibitors of tumour cell migration: Exploring structural change in and on the macrocyclic ring
Lo Re, Daniele; Zhou, Ying; Mucha, Joanna; Jones, Leigh F.; Leahy, Lorraine; Santocanale, Corrado; Krol, Magdalena; Murphy, Paul V. (Wiley, 2015-11-04)Migrastatin and isomigrastatin analogues have been synthesised in order to contribute to structure-activity studies on tumour cell migration inhibitors. These include macrocycles varying in ring size, functionality and ... -
Synthesis of migrastatin analogues as inhibitors of tumour cell migration: exploring structural change in and on the macrocyclic ring
Santocanale, Corrado; Leahy, Lorraine; Jones, Leigh; Zhou, Ling; Murphy, Paul V. (Wiley, 2015-11-04)Migrastatin and isomigrastatin analogues have been synthesised in order to contribute to structure-activity studies on tumour cell migration inhibitors. These include macrocycles varying in ring size, functionality and ...