Now showing items 1-3 of 3

    • Performance review of multiple reference versus time domain optical coherence tomography 

      Neuhaus, Kai; McNamara, Paul M.; Alexandrov, Sergey; O'Gorman, Seán; Hogan, Josh; Wilson, Carol; Leahy, Martin J. (IEEE, 2018-04-19)
      We present a detailed characterization of noise sources in multiple reference optical coherence tomography (MR-OCT) compared to time-domain OCT (TD-OCT). The noise characteristics were modeled based on the TD-OCT noise ...
    • Spatial frequency domain correlation mapping optical coherence tomography for nanoscale structural characterization 

      Alexandrov, Sergey; McNamara, Paul M.; Das, Nandan; Zhou, Yi; Lynch, Gillian; Hogan, Josh; Leahy, Martin (AIP Publishing, 2019-09-16)
      Most of the fundamental pathological processes in living tissues exhibit changes at the nanoscale. Noninvasive, label-free detection of structural changes in biological samples pose a significant challenge to both researchers ...
    • Ultra-sensitive label free imaging below the resolution limit 

      Alexandrov, Sergey; McGrath, James; Sheppard, Colin J. R.; Boccafoschi, Francesca; Giannini, Cinzia; Sibillano, Teresa; Subhash, Hrebesh; Hogan, Josh; Leahy, James J. (SPIE (Society of Photo-optical Instrumentation Engineers) Digital Library, 2019-02-02)
      Almost all known nanoscopy methods rely upon the contrast created by fluorescent labels attached to the object of interest. This causes limitations on their applicability to in vivo imaging. A new label-free spectral ...